Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16709659 | 0.95 | LMNA (0.40) | LMNASMN1; SMN2KDM4EMAPTPKM | |
| SCHEMBL16709709 | 0.95 | LMNA (0.40) | LMNASMN1; SMN2KDM4EMAPTPKM | |
| SCHEMBL3684095 | 0.88 | PTGER3 (0.43) | LMNASMN1; SMN2KDM4EMAPTPKM | |
| SCHEMBL16709696 | 0.86 | MAOA (0.41) | LMNAKDM4EMAPTMAPK1KMT2A | |
| SCHEMBL16709764 | 0.83 | LMNA (0.41) | LMNASMN1; SMN2KDM4EMAPTPKM | |
| SCHEMBL16709701 | 0.77 | SLC6A4 (0.36) | ALDH1A1CYP1A2 | |
| SCHEMBL761802 | 0.77 | LMNA (0.57) | LMNASMN1; SMN2KDM4EMAPTPKM | |
| SCHEMBL30832956 | 0.77 | LMNA (0.57) | LMNASMN1; SMN2KDM4EMAPTPKM | |
| SCHEMBL16709761 | 0.77 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2KDM4EMAPTPKM | |
| SCHEMBL30548745 | 0.75 | MAP2K2 (0.48) | LMNASMN1; SMN2MAP2K2MAP2K1HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015068839-A1 | POLYMERIZABLE COMPOUND, RESIN COMPOSITION USING SAME, CURED RESIN, AND OPTICAL MATERIAL | 新日鉄住金化学株式会社 | 2015-05-14 | — | — | WO | disclosed |