SCHEMBL761802

SCHEMBL761802

c1ccc2cc(Sc3ccc4ccccc4c3)ccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
MAP2K2 P36507 2/20 0.53
MAP2K1 Q02750 2/20 0.53
HAO1 Q9UJM8 1/20 0.53
SIRT2 Q8IXJ6 1/20 0.50
SIRT1 Q96EB6 1/20 0.50
SIRT3 Q9NTG7 1/20 0.50
CYP2A6 P11509 6/20 0.48
CYP1A2 P05177 3/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
ALDH1A1 P00352 1/20 0.48
CYP3A4 P08684 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
ALOX12 P18054 1/20 0.47
G6PD P11413 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30832956 1.00 LMNA (0.57) LMNASMN1; SMN2MAP2K2MAP2K1HAO1
SCHEMBL3281214 0.92 LMNA (0.52) LMNASMN1; SMN2MAP2K2MAP2K1HAO1
SCHEMBL11300299 0.92 ALDH1A1 (0.50) LMNASMN1; SMN2MAP2K2MAP2K1HAO1
SCHEMBL30548745 0.87 MAP2K2 (0.48) LMNASMN1; SMN2MAP2K2MAP2K1HAO1
SCHEMBL8514752 0.86 LMNA (0.47) LMNASMN1; SMN2MAP2K2MAP2K1HAO1
SCHEMBL12952450 0.86 LMNA (0.47) LMNASMN1; SMN2MAP2K2MAP2K1HAO1
SCHEMBL8563632 0.86 CYP3A4 (0.61) LMNASMN1; SMN2MAP2K2MAP2K1HAO1
SCHEMBL14176682 0.86 CYP2A6 (0.60) LMNASMN1; SMN2MAP2K2MAP2K1HAO1
SCHEMBL7708311 0.85 MAOA (0.48) LMNASMN1; SMN2MAP2K2MAP2K1HAO1
SCHEMBL8561255 0.84 MAP2K2 (0.47) LMNASMN1; SMN2MAP2K2MAP2K1HAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303150-A High-efficiency narrow-half-peak-width aggregation state luminescent material 苏州大学 2020-06-19 CN claimed
CN-116041153-B Direct cross coupling method of aryl thioether and aryl bromine 南京工业大学 2024-05-24 CN disclosed
US-20240152047-A1 HIGH REFRACTIVE INDEX MATERIALS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-05-09 US disclosed
CN-114478150-B S-deuterated methyl-aryl sulfonyl thioester compound and synthetic method and application thereof 浙江工业大学 2024-04-09 CN disclosed
CN-116041153-A Direct cross coupling method of aryl thioether and aryl bromine 南京工业大学 2023-05-02 CN disclosed
CN-110540525-B Synthetic method of 3-thioether-group quinoxalinone compound 广西师范大学 2022-11-22 CN disclosed
CN-114591290-A Preparation method of substituted benzo [ B ] naphthalene benzene [2, 3-D ] thiophene derivative and derivative 陕西维世诺新材料有限公司 2022-06-07 CN disclosed
CN-114478150-A S-deuterated methyl-aryl sulfonyl thioester compound and synthesis method and application thereof 浙江工业大学 2022-05-13 CN disclosed
CN-111303150-B High-efficiency narrow-half-peak-width aggregation state luminescent material 苏州大学 2021-10-19 CN disclosed
CN-110483349-B Preparation method of alkyl thioether 中国科学院兰州化学物理研究所 2021-01-12 CN disclosed
US-4339611-A BUTANOL, BUTANAL, COBALT, IODINE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-07-13 US disclosed
US-4304883-A DICYCLOPENTADIENE-MODIFIED ALKYD RESIN, UNSATURATED MONOEPOXIDE HITACHI CHEMICAL COMPANY, LTD. (JP) 1981-12-08 US disclosed
US-4303759-A REACTIVE SULFUR COMPOUND DECOMPOSES PEROXYL RADICAL AIR PRODUCTS AND CHEMICALS, INC. (US) 1981-12-01 US disclosed
US-4301063-A ETHYLENE HOMOPOLYMER AND COPOLYMERS UNION CARBIDE CORPORATION (US) 1981-11-17 US disclosed
US-4044056-A Symmetrical aromatic sulfide production PHILLIPS PETROLEUM COMPANY (US) 1977-08-23 US disclosed
US-4026859-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US disclosed
US-4026860-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US disclosed
US-4026861-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US disclosed
US-4002645-A Bis aromatic anhydrides RAYCHEM CORPORATION (US) 1977-01-11 US disclosed
US-3974114-A CALCIUM AND LITHIUM STEARATE UNION CARBIDE CORPORATION (US) 1976-08-10 US disclosed