Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TYMS | P04818 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | RHEB | Q15382 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16709697 | 0.88 | LMNA (0.41) | PTGER3MAP2K2MAP2K1HAO1SMN1; SMN2 | |
| SCHEMBL16709659 | 0.83 | LMNA (0.40) | PTGER3MAP2K2MAP2K1HAO1SMN1; SMN2 | |
| SCHEMBL16709709 | 0.83 | LMNA (0.40) | PTGER3MAP2K2MAP2K1HAO1SMN1; SMN2 | |
| SCHEMBL3674814 | 0.82 | PTGER3 (0.45) | PTGER3MAP2K2MAP2K1HAO1SMN1; SMN2 | |
| SCHEMBL31241186 | 0.82 | PTGER3 (0.45) | PTGER3MAP2K2MAP2K1HAO1SMN1; SMN2 | |
| SCHEMBL30548745 | 0.80 | MAP2K2 (0.48) | MAP2K2MAP2K1HAO1SMN1; SMN2LMNA | |
| SCHEMBL2575108 | 0.79 | ALDH1A1 (0.41) | SMN1; SMN2LMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL711434 | 0.78 | ALDH1A1 (0.48) | LMNAKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL16709764 | 0.77 | LMNA (0.41) | PTGER3MAP2K2MAP2K1HAO1SMN1; SMN2 | |
| SCHEMBL28853123 | 0.76 | HDAC1 (0.54) | SMN1; SMN2LMNARHEBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718849-B2 | Sulfur chelated ruthenium compounds useful as olefin metathesis catalysts | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2017-08-01 | — | — | US | disclosed |
| US-20140155511-A1 | SULFUR CHELATED RUTHENIUM COMPOUNDS USEFUL AS OLEFIN METATHESIS CATALYSTS | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2014-06-05 | — | — | US | disclosed |
| US-8513151-B2 | Sulfur chelated ruthenium compounds useful as olefin metathesis catalysts | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IS) | 2013-08-20 | — | — | US | disclosed |
| US-20100113722-A1 | SULFUR CHELATED RUTHENIUM COMPOUNDS USEFUL AS OLEFIN METATHESIS CATALYSTS | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155511-A1 | SULFUR CHELATED RUTHENIUM COMPOUNDS USEFUL AS OLEFIN METATHESIS CATALYSTS | C1S, SCO2, AP1S1 | PTGER3 3717/4885MAP2K2 1921/4885MAP2K1 2039/4885 |
| US-20100113722-A1 | SULFUR CHELATED RUTHENIUM COMPOUNDS USEFUL AS OLEFIN METATHESIS CATALYSTS | C1S, SCO2, AP1S1 | PTGER3 3717/4885MAP2K2 1921/4885MAP2K1 2039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.