Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13484060 | 0.87 | USP2 (0.40) | HTTUSP2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13790799 | 0.85 | USP2 (0.39) | HTTALDH1A1USP2CYP1A2CYP3A4 | |
| SCHEMBL13978960 | 0.84 | USP2 (0.42) | HTTALDH1A1USP2CYP1A2CYP3A4 | |
| SCHEMBL430465 | 0.84 | USP2 (0.55) | HTTMEN1KMT2AUSP2CYP1A2 | |
| SCHEMBL13790470 | 0.82 | USP2 (0.37) | HTTUSP2LPAR5HSD17B10CASR | |
| SCHEMBL16948106 | 0.81 | HTT (0.34) | HTTUSP2LPAR5 | |
| SCHEMBL9927969 | 0.81 | KDM4E (0.39) | HTTALDH1A1KMT2AUSP2CYP1A2 | |
| SCHEMBL20052035 | 0.81 | HTT (0.37) | HTTUSP2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL29179076 | 0.81 | USP2 (0.43) | HTTALDH1A1USP2CYP1A2CYP3A4 | |
| SCHEMBL13484063 | 0.81 | USP2 (0.40) | HTTALDH1A1USP2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961352-B2 | Crosslinked aminosilicone polymer and methods for its preparation and use | DOW SILICONES CORPORATION (US) | 2021-03-30 | — | — | US | disclosed |
| US-20150133294-A1 | CHROMATOGRAPHIC MATERIALS | WATERS TECHNOLOGIES CORPORATION (US) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133294-A1 | CHROMATOGRAPHIC MATERIALS | HAX1, CXCR1, YBX1 | HTT 3338/4885MEN1 1378/4885ALDH1A1 1859/4885 |
| US-10961352-B2 | Crosslinked aminosilicone polymer and methods for its preparation and use | ALG3, CUTA, POLR1C | HTT 613/4885MEN1 1509/4885ALDH1A1 2901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.