SCHEMBL430465

SCHEMBL430465

CO[Si](CCCOCC(O)CO)(OC)OC

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.55
LMNA P02545 3/20 0.39
CYP1A2 P05177 2/20 0.39
AGTR1 P30556 1/20 0.39
HTT P42858 1/20 0.37
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
PLA2G2C Q5R387 1/20 0.33
LPAR5 Q9H1C0 1/20 0.33
HSD17B10 Q99714 1/20 0.32
KDM4E B2RXH2 1/20 0.31
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CASR P41180 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13484060 0.89 USP2 (0.40) USP2LMNACYP1A2HTTLPAR5
SCHEMBL13790799 0.87 USP2 (0.39) USP2LMNACYP1A2HTTLPAR5
SCHEMBL428119 0.85 USP2 (0.55) USP2LMNACYP1A2AGTR1HTT
SCHEMBL13978960 0.85 USP2 (0.42) USP2LMNACYP1A2HTTLPAR5
SCHEMBL16710539 0.84 HTT (0.56) USP2CYP1A2HTTLPAR5HSD17B10
SCHEMBL14089863 0.84 USP2 (0.53) USP2LMNACYP1A2AGTR1HTT
SCHEMBL16588236 0.84 USP2 (0.53) USP2LMNACYP1A2AGTR1HTT
SCHEMBL25638703 0.84 USP2 (0.53) USP2LMNACYP1A2AGTR1HTT
SCHEMBL7736607 0.84 USP2 (0.37) USP2LMNACYP1A2AGTR1TSHR
SCHEMBL13790470 0.84 USP2 (0.37) USP2HTTLPAR5HSD17B10CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107849068-B Method for preparing polyhedral oligomeric silsesquioxanes 株式会社LG化学 2020-09-11 CN claimed
US-10501583-B2 Method for preparing polyhedral oligomeric silsesquioxane LG CHEM, LTD. (KR) 2019-12-10 US claimed
WO-2019079144-A1 NON-TOXIC HIGH DENSITY FLUID FOR COMPLETION APPLICATIONS Terves Inc. (US) 2019-04-25 WO claimed
US-20190112516-A1 Non-Toxic High-Density Fluid For Completion Applications TERVES, LLC 2019-04-18 US claimed
US-20180201734-A1 METHOD FOR PREPARING POLYHEDRAL OLIGOMERIC SILSESQUIOXANE LG CHEM, LTD. (KR) 2018-07-19 US claimed
US-6452573-B1 Liquid crystal device comprising anchoring means on at least one confinement plate providing a degenerated orientation NEMOPTIC, S.A. (FR) 2002-09-17 US claimed
CN-1228168-A Liquid crystal device comprising means for anchoring on at least one confinement plate producing a degenerate orientation CENTRE NAT RECH SCIENT (FR) 1999-09-08 CN claimed
EP-0912914-A1 LIQUID CRYSTAL DEVICE COMPRISING ANCHORING MEANS ON AT LEAST ONE CONFINEMENT PLATE PROVIDING A DEGENERATED ORIENTATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1999-05-06 EP claimed
WO-1998050821-A1 LIQUID CRYSTAL DEVICE COMPRISING ANCHORING MEANS ON AT LEAST ONE CONFINEMENT PLATE PROVIDING A DEGENERATED ORIENTATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1998-11-12 WO claimed
JP-11116681-A None JP disclosed
CN-118382664-A Condensation curable composition 迈图高新材料公司 2024-07-23 CN disclosed
US-11914295-B2 Thermosetting iodine- and silicon-containing material, composition containing the material for forming resist underlayer film for EUV lithography, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-02-27 US disclosed
US-20230333472-A1 THERMOSETTING IODINE- AND SILICON-CONTAINING MATERIAL, COMPOSITION CONTAINING THE MATERIAL FOR FORMING RESIST UNDERLAYER FILM FOR EUV LITHOGRAPHY, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-19 US disclosed
US-20230305405-A1 COMPOSITION FOR FORMING SILICON-CONTAINING METAL HARD MASK AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-28 US disclosed
CN-1228168-A Liquid crystal device comprising means for anchoring on at least one confinement plate producing a degenerate orientation CENTRE NAT RECH SCIENT (FR) 1999-09-08 CN disclosed
EP-0912914-A1 LIQUID CRYSTAL DEVICE COMPRISING ANCHORING MEANS ON AT LEAST ONE CONFINEMENT PLATE PROVIDING A DEGENERATED ORIENTATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1999-05-06 EP disclosed
JP-H11116681-A POLYMETHYLSILYLSESQUIOXANE PARTICLE AND DISPERSION OF THE SAME IN HYDROPHILIC SOLVENT TAKEMOTO OIL & FAT CO LTD 1999-04-27 JP disclosed
WO-1998050821-A1 LIQUID CRYSTAL DEVICE COMPRISING ANCHORING MEANS ON AT LEAST ONE CONFINEMENT PLATE PROVIDING A DEGENERATED ORIENTATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1998-11-12 WO disclosed
US-5357024-A Method for preparing a polysiloxane and titanate composition for high refractive index coatings ESSILOR INTERNATIONAL (FR) 1994-10-18 US disclosed
US-4770781-A CHROMATOGRAPHY MERCK & CO., INC. (US) 1988-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230333472-A1 THERMOSETTING IODINE- AND SILICON-CONTAINING MATERIAL, COMPOSITION CONTAINING THE MATERIAL FOR FORMING RESIST UNDERLAYER FILM FOR EUV LITHOGRAPHY, AND PATTERNING PROCESS RPS4X, SIK3, MLX USP2 731/4885LMNA 2563/4885CYP1A2 2955/4885
US-11914295-B2 Thermosetting iodine- and silicon-containing material, composition containing the material for forming resist underlayer film for EUV lithography, and patterning process RPS4X, SIK3, MLX USP2 731/4885LMNA 2563/4885CYP1A2 2955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.