Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3639223 | 0.83 | P2RX7 (0.42) | P2RX7MKNK1MKNK2 | |
| SCHEMBL462122 | 0.81 | CASP1 (0.63) | P2RX7CASP1HPGD | |
| SCHEMBL13044544 | 0.74 | KMT2A (0.44) | P2RX7CASP1HPGD | |
| SCHEMBL6178284 | 0.74 | P2RX7 (0.43) | P2RX7MKNK1MKNK2 | |
| SCHEMBL11072786 | 0.73 | P2RX7 (0.40) | P2RX7MKNK1MKNK2 | |
| SCHEMBL25512311 | 0.73 | MMP2 (0.43) | P2RX7MKNK1MKNK2 | |
| SCHEMBL6274638 | 0.71 | KDM4E (0.47) | HPGD | |
| SCHEMBL8591958 | 0.71 | P2RX7 (0.45) | P2RX7MKNK1MKNK2 | |
| SCHEMBL30360466 | 0.71 | KDM4E (0.47) | HPGD | |
| SCHEMBL23489779 | 0.71 | P2RX7 (0.39) | P2RX7HPGDMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614061-B1 | QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2015-05-20 | — | — | EP | disclosed |