Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SAT1 | P21673 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 4/20 | 0.37 |
| ▸ | MMP2 | P08253 | 4/20 | 0.37 |
| ▸ | MMP3 | P08254 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid Monomethyl Ester SCHEMBL16774559 | 0.86 | TP53 (0.44) | TP53SAT1MMP1MMP2MMP3 | |
| Propane SCHEMBL4629637 | 0.83 | CA2 (0.35) | MMP1MMP2MMP3MMP8PLA2G2A | |
| Alcohol SCHEMBL7622017 | 0.80 | PPARD (0.39) | MMP1MMP2MMP3MMP8PLA2G2A | |
| SCHEMBL16713982 | 0.80 | ANPEP (0.45) | SAT1MMP1MMP2MMP3MMP9 | |
| Diethylamine SCHEMBL29187214 | 0.80 | TP53 (0.57) | TP53SAT1MMP1MMP2MMP3 | |
| Diethylamine SCHEMBL320756 | 0.80 | TP53 (0.57) | TP53SAT1MMP1MMP2MMP3 | |
| Diethylamine SCHEMBL1203507 | 0.80 | TP53 (0.57) | TP53SAT1MMP1MMP2MMP3 | |
| Diethylamine SCHEMBL9484949 | 0.80 | TP53 (0.57) | TP53SAT1MMP1MMP2MMP3 | |
| SCHEMBL47754 | 0.80 | — | — | |
| SCHEMBL28223995 | 0.80 | CA2 (0.43) | MMP1MMP2MMP8MMP9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9472829-B2 | Method for stabilizing LiPF6, electrolyte solution for nonaqueous secondary batteries having excellent thermal stability, and nonaqueous secondary battery having excellent thermal stability | TOSOH F-TECH, INC. (JP) | 2016-10-18 | — | — | US | disclosed |
| US-20150140445-A1 | METHOD FOR STABILIZING LIPF6, ELECTROLYTE SOLUTION FOR NONAQUEOUS SECONDARY BATTERIES HAVING EXCELLENT THERMAL STABILITY, AND NONAQUEOUS SECONDARY BATTERY HAVING EXCELLENT THERMAL STABILITY | TOSOH F-TECH, INC. (JP) | 2015-05-21 | — | — | US | disclosed |
| CN-104364861-A | Flame-retardant electrolytic capacitor | NIPPON CHEMICON | 2015-02-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150140445-A1 | METHOD FOR STABILIZING LIPF6, ELECTROLYTE SOLUTION FOR NONAQUEOUS SECONDARY BATTERIES HAVING EXCELLENT THERMAL STABILITY, AND NONAQUEOUS SECONDARY BATTERY HAVING EXCELLENT THERMAL STABILITY | ELOVL6, ABHD6, NAF1 | TP53 1841/4885SAT1 585/4885MMP1 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.