SCHEMBL16715035

SCHEMBL16715035

CC(C)(C)OC(=O)N1C(=O)CC[C@H]1C(=O)NNC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KLK7 P49862 3/20 0.37
WNT3 P56703 1/20 0.36
SFRP1 Q8N474 1/20 0.36
STS P08842 1/20 0.36
GPR119 Q8TDV5 2/20 0.35
JAK2 O60674 1/20 0.35
JAK1 P23458 1/20 0.35
AGTR2 P50052 1/20 0.34
KLK5 Q9Y337 1/20 0.34
YAP1 P46937 1/20 0.34
PARP1 P09874 1/20 0.34
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KCNA5 P22460 1/20 0.33
GHSR Q92847 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16714976 1.00 KLK7 (0.37) KLK7WNT3SFRP1STSGPR119
SCHEMBL16612125 0.88 KCNA5 (0.35) KCNA5
SCHEMBL16611362 0.88 KCNA5 (0.35) KCNA5
SCHEMBL15366663 0.86 KMT2A (0.41) STSAGTR2KMT2AL3MBTL1
SCHEMBL20402402 0.86 STS (0.43) STSGPR119JAK2JAK1YAP1
SCHEMBL15799761 0.86 STS (0.43) STSGPR119JAK2JAK1YAP1
SCHEMBL15799760 0.86 STS (0.43) STSGPR119JAK2JAK1YAP1
SCHEMBL15208521 0.86 STS (0.43) STSGPR119JAK2JAK1YAP1
SCHEMBL15364635 0.85 STS (0.51) STSGPR119JAK2JAK1YAP1
SCHEMBL15364851 0.85 YAP1 (0.41) STSGPR119JAK2JAK1YAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12103928-B2 Processes for preparing a diazabicyclooctane compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2024-10-01 US disclosed
US-20230331724-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND MEIJI SEIKA PHARMA CO., LTD. (JP) 2023-10-19 US disclosed
US-11731971-B2 Processes for preparing a diazabicyclooctane compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2023-08-22 US disclosed
US-9181250-B2 Beta-lactamase inhibitor and process for preparing the same MEIJI SEIKA PHARMA CO., LTD. (JP) 2015-11-10 US disclosed
US-20150141401-A1 NOVEL BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME MEIJI SEIKA PHARMA CO., LTD. (JP) 2015-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731971-B2 Processes for preparing a diazabicyclooctane compound FN1, BMP1, AZI2 KLK7 4463/4885WNT3 3359/4885SFRP1 585/4885
US-20150141401-A1 NOVEL BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME ME1, FN1, FNTB KLK7 4730/4885WNT3 1023/4885SFRP1 2309/4885
US-20230331724-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND FN1, BMP1, AZI2 KLK7 4463/4885WNT3 3359/4885SFRP1 585/4885
US-12103928-B2 Processes for preparing a diazabicyclooctane compound FN1, BMP1, AZI2 KLK7 4463/4885WNT3 3359/4885SFRP1 585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.