Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16715268 | 0.89 | HPGD (0.50) | TACR1BCHEGPR139ALDH1A1SLC6A9 | |
| SCHEMBL414657 | 0.84 | ACP3 (0.43) | GPR139ALDH1A1ATML3MBTL1SLC6A9 | |
| SCHEMBL381185 | 0.83 | ACP3 (0.47) | TACR1GPR139ALDH1A1ATML3MBTL1 | |
| SCHEMBL15170368 | 0.83 | ACP3 (0.47) | TACR1GPR139ALDH1A1ATML3MBTL1 | |
| SCHEMBL794506 | 0.83 | ALDH1A1 (0.42) | TACR1BCHEGPR139ALDH1A1SLC6A9 | |
| SCHEMBL381695 | 0.80 | OPRM1 (0.43) | TACR1BCHEGPR139ALDH1A1ATM | |
| SCHEMBL16674214 | 0.79 | PNMT (0.52) | TACR1GPR139ALDH1A1ATML3MBTL1 | |
| SCHEMBL16715321 | 0.78 | CNR2 (0.41) | TACR1ALDH1A1L3MBTL1POLBCYP1A2 | |
| SCHEMBL19244872 | 0.77 | OPRM1 (0.48) | TACR1BCHEGPR139ALDH1A1POLB | |
| SCHEMBL10129770 | 0.77 | TACR1 (0.48) | TACR1BCHEGPR139ALDH1A1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9034855-B2 | Substituted phenylacetate and phenylpropane amides and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-05-19 | — | — | US | disclosed |