Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.39 |
| ▸ | MICA | Q29983 | 2/20 | 0.39 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793329 | 0.88 | TACR1 (0.41) | ALDH1A1POLBCYP3A4MEN1CYP1A2 | |
| SCHEMBL16715277 | 0.87 | PPARG (0.40) | ALDH1A1POLBCYP3A4MEN1CYP1A2 | |
| SCHEMBL794179 | 0.84 | ALDH1A1 (0.42) | ALDH1A1POLBCYP3A4MEN1CYP1A2 | |
| SCHEMBL793948 | 0.84 | VNN1 (0.45) | CYP3A4GPR139TSHR | |
| SCHEMBL16715280 | 0.83 | TACR1 (0.44) | ALDH1A1POLBCYP3A4MEN1CYP1A2 | |
| SCHEMBL794263 | 0.81 | ALDH1A1 (0.41) | ALDH1A1POLBCYP3A4MEN1CYP1A2 | |
| SCHEMBL414657 | 0.79 | ACP3 (0.43) | ALDH1A1POLBCYP3A4MEN1CYP1A2 | |
| SCHEMBL15947806 | 0.78 | ALDH1A1 (0.46) | ALDH1A1POLBCYP3A4MEN1CYP1A2 | |
| SCHEMBL15170368 | 0.77 | ACP3 (0.47) | ALDH1A1POLBCYP3A4MEN1CYP1A2 | |
| SCHEMBL381185 | 0.77 | ACP3 (0.47) | ALDH1A1POLBCYP3A4MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9034855-B2 | Substituted phenylacetate and phenylpropane amides and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| EP-2616448-A1 | SUBSTITUTED PHENYLACETATE AND PHENYLPROPANE AMIDES AND USE THEREOF | Bayer Intellectual Property GmbH (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035075-A1 | SUBSTITUTED PHENYLACETATE AND PHENYLPROPANE AMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-22 | — | — | WO | disclosed |