Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1549076 | 0.84 | CSNK2A1 (0.53) | CSNK2A1MEN1KMT2AHSD17B1CYP1A2 | |
| SCHEMBL31534041 | 0.82 | HSD17B1 (0.42) | CSNK2A1MEN1KMT2ASRCHSD17B1 | |
| SCHEMBL9217873 | 0.80 | HSD17B1 (0.58) | CSNK2A1MEN1KMT2AHSD17B1NPC1 | |
| SCHEMBL696316 | 0.79 | ALDH1A1 (0.50) | MEN1KMT2AHSD17B1RAB9ACYP1A2 | |
| SCHEMBL5447109 | 0.79 | CES2 (0.47) | MEN1KMT2AHSD17B1GABRPGABRD | |
| SCHEMBL4604668 | 0.78 | PARP1 (0.42) | CSNK2A1MEN1KMT2AHSD17B1NPC1 | |
| SCHEMBL14808369 | 0.78 | HSD17B1 (0.40) | CSNK2A1MEN1KMT2ASRCHSD17B1 | |
| SCHEMBL8185535 | 0.78 | NFE2L2 (0.54) | CSNK2A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL30122043 | 0.78 | NFE2L2 (0.54) | CSNK2A1MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5614036 | 0.77 | PARP1 (0.41) | CSNK2A1MEN1KMT2AHSD17B1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611802-B1 | BICYCLIC AZA-HETEROCYCLES AND THEIR USE | BAYER IP GMBH (DE) | 2016-02-24 | — | — | EP | disclosed |
| EP-2611802-A1 | BICYCLIC AZA HETEROCYCLES, AND USE THEREOF | Bayer Intellectual Property GmbH (DE) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012028647-A1 | BICYCLIC AZA HETEROCYCLES, AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-08 | — | — | WO | disclosed |