Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13220245 | 0.81 | GHSR (0.53) | CHRNB2CHRNA4GHSRPOLB | |
| SCHEMBL13220243 | 0.77 | POLB (0.59) | CHRNB2CHRNA4GHSRPOLBSLC18A3 | |
| SCHEMBL19715652 | 0.75 | ALDH1A1 (0.49) | SLC6A4LMNAALDH1A1BLMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4533102 | 0.75 | ALDH1A1 (0.49) | SLC6A4LMNAALDH1A1BLMSMN1; SMN2 | |
| SCHEMBL11470451 | 0.74 | POLB (0.60) | SLC6A4POLB | |
| SCHEMBL29278481 | 0.72 | SLC6A4 (0.31) | SLC6A4 | |
| SCHEMBL18661418 | 0.72 | ALDH1A1 (0.42) | LMNAALDH1A1BLMSMN1; SMN2CARM1 | |
| SCHEMBL19576752 | 0.71 | TAAR1 (0.45) | SLC6A4ALDH1A1SMN1; SMN2SLC18A3 | |
| SCHEMBL14045705 | 0.71 | ALDH1A1 (0.52) | LMNAALDH1A1BLMSMN1; SMN2SLC18A3 | |
| SCHEMBL21413769 | 0.71 | CARM1 (0.47) | SLC6A4LMNAALDH1A1BLMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403831-B1 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLOÝ3,4-b¨PYRIDINE | ITALIANA SINT SPA (IT) | 2015-05-20 | — | — | EP | disclosed |