SCHEMBL8940199

SCHEMBL8940199

NC(=S)N(Cc1ccccc1)c1ccc(N)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
NPC1 O15118 1/20 0.44
GLA P06280 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
PAX8 Q06710 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MAOB P27338 3/20 0.42
MAOA P21397 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MGLL Q99685 1/20 0.41
TSPO P30536 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8612544 0.93 ALDH1A1 (0.49) ALDH1A1NPC1GLAHTTRAB9A
SCHEMBL16718679 0.89 ALDH1A1 (0.53) ALDH1A1NPC1GLAHTTRAB9A
SCHEMBL8616953 0.86 SLC22A2 (0.47) ALDH1A1NPC1GLAHTTRAB9A
SCHEMBL4443147 0.82 NPC1 (0.54) ALDH1A1NPC1GLAHTTRAB9A
SCHEMBL10532358 0.81 NPC1 (0.59) ALDH1A1NPC1GLAHTTRAB9A
SCHEMBL8615325 0.81 ALDH1A1 (0.47) ALDH1A1NPC1GLAHTTRAB9A
SCHEMBL8940192 0.79 CRHBP (0.54) ALDH1A1HTTSMN1; SMN2KDM4ECYP1A2
SCHEMBL6463846 0.77 ALDH1A1 (0.51) ALDH1A1NPC1GLAHTTRAB9A
SCHEMBL8614127 0.75 AKT1 (0.57) NPC1HTTRAB9AKDM4EMAPT
SCHEMBL1498777 0.74 CYP2C19 (0.64) ALDH1A1GLASMN1; SMN2MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5567411-A ADMINISTERING TO A WARM-BLOODED ANIMAL TO OBTAIN A MAGNETIC RESONANCE IMAGE OF SUBJECT STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) 1996-10-22 US disclosed