Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16718679 | 0.86 | ALDH1A1 (0.53) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL8612544 | 0.82 | ALDH1A1 (0.49) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL28432596 | 0.80 | ALDH1A1 (0.55) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL1385749 | 0.78 | ALDH1A1 (0.62) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL28128819 | 0.78 | NPC1 (0.53) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL6463842 | 0.78 | NPC1 (0.53) | ALDH1A1NPC1GLAHTTRAB9A | |
| Carbamic Acid SCHEMBL6468271 | 0.78 | NPC1 (0.62) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL8615325 | 0.78 | ALDH1A1 (0.47) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL319905 | 0.78 | MGLL (0.59) | ALDH1A1MGLLGAATSHR | |
| Hydrochloric Acid SCHEMBL27540694 | 0.77 | NPC1 (0.61) | ALDH1A1NPC1GLAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050203176-A1 | Carbamates as HIV anti-viral agents | WYETH (US) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203176-A1 | Carbamates as HIV anti-viral agents | RNASEH1, CTSH, RNASE1 | ALDH1A1 2591/4885NPC1 1339/4885GLA 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.