Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831318 | 0.87 | FFAR4 (0.62) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| SCHEMBL18677287 | 0.87 | FFAR4 (0.62) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| SCHEMBL8831544 | 0.87 | ALDH1A1 (0.56) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| SCHEMBL16342953 | 0.87 | FFAR4 (0.62) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| SCHEMBL8831180 | 0.87 | FFAR4 (0.62) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| SCHEMBL8831205 | 0.87 | FFAR4 (0.62) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| SCHEMBL10231901 | 0.84 | GABRP (0.41) | FFAR4FFAR1ALDH1A1GPR84TSHR | |
| SCHEMBL8831169 | 0.84 | FFAR4 (0.58) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| SCHEMBL27679136 | 0.82 | LMNA (0.46) | FFAR4FFAR1ALDH1A1GPR84TSHR | |
| Palmitic Acid SCHEMBL28126905 | 0.82 | FFAR4 (0.56) | FFAR4FFAR1ALDH1A1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473550-B | EGF (A) analogues with fatty acid substituents | 诺和诺德股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| EP-3402811-B1 | EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS | NOVO NORDISK AS (DK) | 2022-03-30 | — | — | EP | disclosed |
| US-20200407409-A1 | EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS | CHEN JIANHE (CN) | 2020-12-31 | — | — | US | disclosed |
| CN-105722526-B | Selective PYY compounds and uses thereof | 诺和诺德股份有限公司 | 2020-12-08 | — | — | CN | disclosed |
| US-10822385-B2 | EGF(A) analogues with fatty acid substituents | NOVO NORDISK A/S (DK) | 2020-11-03 | — | — | US | disclosed |
| EP-3068421-B1 | SELECTIVE PYY COMPOUNDS AND USES THEREOF | NOVO NORDISK AS (DK) | 2019-04-17 | — | — | EP | disclosed |
| US-10246497-B2 | Selective PYY compounds and uses thereof | NOVO NORDISK A/S (DK) | 2019-04-02 | — | — | US | disclosed |
| US-20190016768-A1 | EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS | NOVO NORDISK A/S (DK) | 2019-01-17 | — | — | US | disclosed |
| EP-3402811-A1 | EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS | Novo Nordisk A/S (DK) | 2018-11-21 | — | — | EP | disclosed |
| WO-2017121850-A1 | EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS | NOVO NORDISK A/S (DK) | 2017-07-20 | — | — | WO | disclosed |
| US-20160289283-A1 | SELECTIVE PYY COMPOUNDS AND USES THEREOF | NOVO NORDISK (DK) | 2016-10-06 | — | — | US | disclosed |
| EP-3068421-A1 | SELECTIVE PYY COMPOUNDS AND USES THEREOF | Novo Nordisk A/S (DK) | 2016-09-21 | — | — | EP | disclosed |
| US-9085637-B2 | Selective PYY compounds and uses thereof | NOVO NORDISK A/S (DK) | 2015-07-21 | — | — | US | disclosed |
| US-20150152150-A1 | Selective PYY compounds and uses thereof | NOVO NORDISK A/S (DK) | 2015-06-04 | — | — | US | disclosed |
| WO-2015071355-A1 | SELECTIVE PYY COMPOUNDS AND USES THEREOF | NOVO NORDISK A/S (DK) | 2015-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289283-A1 | SELECTIVE PYY COMPOUNDS AND USES THEREOF | NPY1R, NPY5R, NPY2R | FFAR4 150/4885FFAR1 166/4885ALDH1A1 4809/4885 |
| US-20150152150-A1 | Selective PYY compounds and uses thereof | NPY1R, NPY5R, NPY2R | FFAR4 150/4885FFAR1 166/4885ALDH1A1 4809/4885 |
| US-20190016768-A1 | EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS | EGFR, LDLR, FFAR2 | FFAR4 13/4885FFAR1 7/4885ALDH1A1 3672/4885 |
| US-10822385-B2 | EGF(A) analogues with fatty acid substituents | EGFR, LDLR, FFAR2 | FFAR4 13/4885FFAR1 7/4885ALDH1A1 3672/4885 |
| US-20200407409-A1 | EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS | EGFR, LDLR, FFAR2 | FFAR4 13/4885FFAR1 7/4885ALDH1A1 3672/4885 |
| US-10246497-B2 | Selective PYY compounds and uses thereof | NPY1R, NPY5R, NPY2R | FFAR4 150/4885FFAR1 166/4885ALDH1A1 4809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.