Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137738 | 1.00 | HSD11B1 (0.34) | HSD11B1HTR2CMEN1KMT2AALDH1A1 | |
| SCHEMBL6137485 | 0.85 | MEN1 (0.36) | HSD11B1HTR2CMEN1KMT2AALDH1A1 | |
| SCHEMBL8994728 | 0.67 | GAA (0.34) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL5572903 | 0.66 | MEN1 (0.32) | HTR2CMEN1KMT2AL3MBTL1 | |
| 1,2-Dimethoxybenzene SCHEMBL27452731 | 0.57 | CA1 (0.93) | KMT2AALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10571023 | 0.57 | CA1 (0.48) | HSD11B1HTR2CMEN1KMT2AALDH1A1 | |
| SCHEMBL1515163 | 0.56 | HTR2C (0.75) | HTR2CMEN1KMT2AATMCA12 | |
| SCHEMBL28829941 | 0.56 | HTR2C (0.49) | HSD11B1HTR2CMEN1KMT2AALDH1A1 | |
| SCHEMBL476857 | 0.55 | CA1 (0.50) | KMT2AALDH1A1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL56425 | 0.55 | CA1 (0.50) | KMT2AALDH1A1SMN1; SMN2TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068770-A1 | PROCESSES FOR THE PREPARATION OF PYRIMIDINYLCYCLOPENTANE COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073739-A1 | PROCESSES FOR THE PREPARATION OF PYRIMIDINYLCYCLOPENTANE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-05-21 | — | — | WO | disclosed |