Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15967700 | 0.69 | — | — | |
| SCHEMBL6137485 | 0.68 | MEN1 (0.36) | MEN1KMT2AHTR2CL3MBTL1 | |
| SCHEMBL6137738 | 0.66 | HSD11B1 (0.34) | MEN1KMT2AHTR2CL3MBTL1 | |
| SCHEMBL16719320 | 0.66 | HSD11B1 (0.34) | MEN1KMT2AHTR2CL3MBTL1 | |
| SCHEMBL6651864 | 0.66 | SMN1; SMN2 (0.42) | KMT2AHTR2C | |
| SCHEMBL29527648 | 0.66 | SMN1; SMN2 (0.42) | KMT2AHTR2C | |
| SCHEMBL16694568 | 0.64 | CA1 (0.43) | HTR2C | |
| SCHEMBL29527801 | 0.64 | CA1 (0.43) | HTR2C | |
| SCHEMBL8149220 | 0.63 | ROCK2 (0.36) | — | |
| SCHEMBL30829086 | 0.63 | CA1 (0.41) | MEN1KMT2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761548-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006002729-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2006-01-12 | — | — | WO | disclosed |