Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9243485 | 0.71 | TUBB4A (0.35) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8994707 | 0.71 | TUBB4A (0.35) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16719320 | 0.67 | HSD11B1 (0.34) | GAASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL6137485 | 0.66 | MEN1 (0.36) | GAASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL6833825 | 0.60 | NFE2L2 (0.45) | SMN1; SMN2NPC1ALDH1A1MAPTTSHR | |
| SCHEMBL6841051 | 0.60 | NFE2L2 (0.45) | SMN1; SMN2NPC1ALDH1A1MAPTTSHR | |
| SCHEMBL29639264 | 0.59 | HTR2C (0.53) | GAASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL25434306 | 0.59 | CA1 (0.61) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL151213 | 0.59 | CA1 (0.61) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27753904 | 0.59 | CA1 (0.61) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488172-A | Chiral phosphorus compounds | HOFFMANN-LA ROCHE INC. (US) | 1996-01-30 | — | — | US | disclosed |