Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137738 | 0.85 | HSD11B1 (0.34) | MEN1KMT2AHTR2CHSD11B1KDM4E | |
| SCHEMBL16719320 | 0.85 | HSD11B1 (0.34) | MEN1KMT2AHTR2CHSD11B1KDM4E | |
| SCHEMBL5572903 | 0.68 | MEN1 (0.32) | MEN1KMT2AHTR2CL3MBTL1 | |
| SCHEMBL8994728 | 0.66 | GAA (0.34) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL28980582 | 0.60 | HTR2C (0.47) | MEN1KMT2AHTR2CHSD11B1KDM4E | |
| SCHEMBL10571023 | 0.60 | CA1 (0.48) | MEN1KMT2AHTR2CHSD11B1KDM4E | |
| SCHEMBL27560576 | 0.60 | HTR2C (0.59) | MEN1KMT2AHTR2CHTR2AHTR2B | |
| SCHEMBL1515163 | 0.59 | HTR2C (0.75) | MEN1KMT2AHTR2CATM | |
| SCHEMBL28829941 | 0.58 | HTR2C (0.49) | MEN1KMT2AHTR2CHSD11B1KDM4E | |
| SCHEMBL28038759 | 0.58 | HTR2C (0.57) | MEN1KMT2AHTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1199301-B1 | Olefination process to itaconate and succinate derivatives | PFIZER LTD (GB) | 2005-06-08 | — | — | EP | disclosed |
| EP-1199301-A1 | Olefination process to itaconate and succinate derivatives | Pfizer Limited (GB) | 2002-04-24 | — | — | EP | disclosed |