Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802231 | 0.87 | DRD1 (0.45) | DRD1KCNN4KMT2ASMN1; SMN2HTT | |
| SCHEMBL9988560 | 0.79 | CA1 (0.52) | KCNN4KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL16719326 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTPOLBCYP3A4 | |
| SCHEMBL7689025 | 0.76 | KCNN4 (0.42) | DRD1KCNN4KMT2ASMN1; SMN2HTT | |
| SCHEMBL13729018 | 0.76 | DRD1 (0.44) | DRD1KCNN4KMT2ASMN1; SMN2HTT | |
| SCHEMBL2373478 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KDM4ECA2MAPT | |
| SCHEMBL5329495 | 0.73 | DRD1 (0.45) | DRD1KCNN4KMT2ASMN1; SMN2HTT | |
| SCHEMBL363528 | 0.73 | CA2 (0.50) | DRD1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL16720357 | 0.73 | DRD1 (0.40) | DRD1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL16720271 | 0.73 | MAPT (0.39) | KMT2ASMN1; SMN2ALDH1A1KDM4ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |