Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 5/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.37 |
| ▸ | BCR | P11274 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.35 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.35 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.35 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.35 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719899 | 0.85 | ABL1 (0.42) | HDAC4HDAC8ABL1ABCB1BCR | |
| SCHEMBL2377417 | 0.80 | HDAC4 (0.55) | HDAC4HDAC8ABL1ABCB1BCR | |
| SCHEMBL16719521 | 0.80 | HSD17B1 (0.40) | CYP3A4KDM1A | |
| SCHEMBL17514939 | 0.78 | CYP1A1 (0.46) | ABL1ABCB1BCRCYP3A4CYP1A1 | |
| SCHEMBL16719654 | 0.78 | KDM4E (0.47) | HDAC4HDAC8HDAC2 | |
| SCHEMBL16719996 | 0.77 | ALOX5 (0.35) | PGR | |
| SCHEMBL16720629 | 0.77 | CYP11B1 (0.44) | HDAC4HDAC8CYP3A4CYP1A1CYP1A2 | |
| SCHEMBL16719852 | 0.76 | ALDH1A1 (0.36) | HDAC4HDAC8ABL1ABCB1BCR | |
| SCHEMBL16720131 | 0.74 | ESR2 (0.47) | — | |
| SCHEMBL9650164 | 0.72 | NPC1 (0.35) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |