Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM4B | O94953 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720261 | 0.79 | CASP6 (0.35) | CASP6ADORA2AKDM4AKDM4BKDM5C | |
| SCHEMBL28003562 | 0.77 | CASP6 (0.41) | CASP6ADORA2AKDM4AKDM4BKDM5C | |
| SCHEMBL7508479 | 0.76 | CASP6 (0.35) | CASP6KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL7855621 | 0.76 | TSHR (0.36) | KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL16719786 | 0.72 | NPC1 (0.38) | — | |
| SCHEMBL16720602 | 0.70 | IDO1 (0.33) | KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL16720102 | 0.69 | MAPT (0.33) | CASP6KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL16720292 | 0.68 | SCN9A (0.34) | — | |
| SCHEMBL27852621 | 0.68 | NOS3 (0.31) | — | |
| SCHEMBL5236635 | 0.67 | PDCD1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |