Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 4/20 | 0.34 |
| ▸ | CLK3 | P49761 | 4/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720066 | 0.82 | HSD17B1 (0.38) | HTR7ADRA2AADRA2BADRA2C | |
| SCHEMBL6638777 | 0.81 | TAAR1 (0.44) | HTR7TAAR1 | |
| SCHEMBL6048501 | 0.75 | BACE1 (0.51) | HTR7HTR1ATAAR1 | |
| SCHEMBL2012496 | 0.74 | ACHE (0.41) | HTR7HTR1ATAAR1PIM1ESR2 | |
| SCHEMBL7812113 | 0.74 | TAAR1 (0.41) | HTR7HTR1ATAAR1PIM1ESR2 | |
| SCHEMBL16719738 | 0.74 | CHRNB2 (0.35) | HTR7HTR1AADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL6048589 | 0.74 | BACE1 (0.50) | HTR7HTR1ATAAR1 | |
| SCHEMBL6331673 | 0.73 | CYP2A6 (0.48) | ADRA2AADRA2BADRA2C | |
| SCHEMBL6339684 | 0.73 | CYP1A2 (0.37) | — | |
| SCHEMBL2430766 | 0.72 | NT5E (0.41) | HTR7HTR1ATAAR1ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |