Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19887491 | 0.74 | AXL (0.53) | AXLNUDT1APPPARP1PARP2 | |
| SCHEMBL15091185 | 0.74 | ALDH1A1 (0.40) | AXLNUDT1PARP1 | |
| SCHEMBL3254758 | 0.73 | HTR3E (0.54) | — | |
| SCHEMBL16417015 | 0.72 | JAK3 (0.44) | AXLNUDT1PARP1PARP2 | |
| SCHEMBL16417007 | 0.70 | JAK3 (0.45) | AXLNUDT1PARP1PARP2 | |
| SCHEMBL4975825 | 0.70 | JAK3 (0.45) | AXLNUDT1PARP1PARP2 | |
| SCHEMBL21178868 | 0.70 | AXL (0.36) | AXLNUDT1BRD4APPPARP1 | |
| SCHEMBL12672907 | 0.69 | MAPK1 (0.51) | — | |
| SCHEMBL5413458 | 0.68 | PIK3CA (0.50) | PARP1PARP2 | |
| SCHEMBL16417018 | 0.68 | HTR3A (0.53) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |