Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719996 | 0.83 | ALOX5 (0.35) | ALOX5CNR1CNR2 | |
| SCHEMBL16719910 | 0.81 | ALOX5 (0.55) | ALOX5TSHRESR2PIK3CANPC1 | |
| SCHEMBL16719521 | 0.79 | HSD17B1 (0.40) | KDM1ACNR1CNR2HCAR1ESR2 | |
| SCHEMBL16720201 | 0.78 | ALOX5 (0.45) | ALOX5TSHRPIK3CAKDM4ENPC1 | |
| SCHEMBL9987901 | 0.77 | HSD17B1 (0.48) | ESR2CA12ALDH1A1CA2LMNA | |
| SCHEMBL16719899 | 0.76 | ABL1 (0.42) | ALOX5KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL16720053 | 0.74 | TSHR (0.45) | ALOX5TSHRPIK3CAKDM4ENPC1 | |
| SCHEMBL16719770 | 0.74 | ESR2 (0.52) | ALOX5TSHRESR2ALDH1A1CA2 | |
| SCHEMBL16719695 | 0.74 | HSD17B1 (0.42) | PIK3CAKDM4ENPC1CA12GMNN | |
| SCHEMBL9987990 | 0.74 | ESR1 (0.42) | ALOX5ESR2PIK3CAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |