Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720523 | 0.79 | HSD17B2 (0.50) | ALDH1A1TSHRPKMMEN1KMT2A | |
| SCHEMBL16720108 | 0.77 | CA2 (0.50) | ALDH1A1PKMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3363833 | 0.74 | ALDH1A1 (0.51) | ALDH1A1ESR1TSHRPKMMEN1 | |
| SCHEMBL30023958 | 0.74 | PTGS1 (0.57) | ALDH1A1ESR1PKMMEN1KMT2A | |
| SCHEMBL12811024 | 0.74 | PTGS1 (0.57) | ALDH1A1ESR1PKMMEN1KMT2A | |
| SCHEMBL27601619 | 0.74 | CA2 (0.57) | ALDH1A1ESR1TSHRPKMMEN1 | |
| SCHEMBL28858446 | 0.73 | ALDH1A1 (0.50) | ALDH1A1ESR1PKMMEN1KMT2A | |
| SCHEMBL29978636 | 0.73 | KMT2A (0.48) | ALDH1A1ESR1PKMMEN1KMT2A | |
| SCHEMBL30916938 | 0.73 | KMT2A (0.48) | ALDH1A1ESR1PKMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28210785 | 0.72 | KMT2A (0.47) | ALDH1A1ESR1PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |