Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720010 | 0.72 | RIPK1 (0.55) | AXLNUDT1 | |
| SCHEMBL16720661 | 0.70 | BRD4 (0.38) | BRD4AXLNUDT1 | |
| SCHEMBL16720494 | 0.70 | TYR (0.46) | BRD4 | |
| SCHEMBL16719974 | 0.68 | AHR (0.40) | BRD4 | |
| SCHEMBL16720891 | 0.68 | NUDT1 (0.51) | AXLNUDT1 | |
| SCHEMBL31065010 | 0.67 | RIPK1 (0.54) | BRD4 | |
| SCHEMBL16719750 | 0.67 | NPC1 (0.50) | — | |
| SCHEMBL14735035 | 0.66 | BRD4 (0.53) | BRD4AXLNUDT1 | |
| SCHEMBL963531 | 0.65 | AXL (0.45) | BRD4AXLNUDT1 | |
| SCHEMBL31276718 | 0.65 | AXL (0.45) | BRD4AXLNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |