Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 0.37 |
| ▸ | MLYCD | O95822 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670795 | 0.81 | AR (0.44) | BRD4MLYCDCREBBPARBRD2 | |
| SCHEMBL1670136 | 0.80 | MLYCD (0.36) | BRD4MLYCDCREBBPBRD2ERN1 | |
| SCHEMBL1670817 | 0.79 | MLYCD (0.40) | BRD4MLYCDCREBBPARBRD2 | |
| SCHEMBL1670383 | 0.74 | BRD4 (0.40) | BRD4MLYCDCREBBPARBRD2 | |
| SCHEMBL1670622 | 0.73 | ERN1 (0.39) | BRD4MLYCDCREBBPARBRD2 | |
| SCHEMBL12800999 | 0.72 | PTGS2 (0.43) | BRD4CREBBPBRD2 | |
| SCHEMBL1682484 | 0.71 | BRD4 (0.40) | BRD4MLYCDCREBBPARBRD2 | |
| SCHEMBL12362813 | 0.69 | BRD4 (0.66) | BRD4MLYCDCREBBPBRD2ERN1 | |
| Hydrochloric Acid SCHEMBL23174957 | 0.67 | BRD4 (0.63) | BRD4MLYCDCREBBPBRD2ERN1 | |
| SCHEMBL1670920 | 0.67 | PTGS2 (0.47) | BRD4CREBBPBRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |