Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | MLYCD | O95822 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 10/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670817 | 0.83 | MLYCD (0.40) | ARMLYCDBRD4BRD2USP30 | |
| SCHEMBL12801015 | 0.83 | MLYCD (0.45) | MLYCDBRD4NPSR1BRD2ESR1 | |
| SCHEMBL1672131 | 0.81 | BRD4 (0.37) | ARMLYCDBRD4BRD2USP30 | |
| SCHEMBL1670622 | 0.79 | ERN1 (0.39) | ARMLYCDBRD4BRD2USP30 | |
| SCHEMBL1670383 | 0.77 | BRD4 (0.40) | ARMLYCDBRD4BRD2USP30 | |
| SCHEMBL1682484 | 0.74 | BRD4 (0.40) | ARMLYCDBRD4BRD2USP30 | |
| SCHEMBL12362813 | 0.72 | BRD4 (0.66) | MLYCDBRD4BRD2ERN1CREBBP | |
| SCHEMBL16194282 | 0.71 | MLYCD (0.43) | ARMLYCDBRD4NPSR1ESR2 | |
| Hydrochloric Acid SCHEMBL23174957 | 0.70 | BRD4 (0.63) | MLYCDBRD4BRD2ERN1CREBBP | |
| SCHEMBL1670920 | 0.70 | PTGS2 (0.47) | BRD4NPSR1BRD2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |