Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498487 | 0.84 | MEN1 (0.54) | KDM4EPOLBALDH1A1CYP2D6TSHR | |
| SCHEMBL3547607 | 0.81 | KDM4E (0.72) | KDM4EPDE4BPOLBALDH1A1CYP2D6 | |
| SCHEMBL29537569 | 0.80 | KDM4E (0.74) | KDM4EPDE4BPOLBALDH1A1CYP2D6 | |
| SCHEMBL14907128 | 0.80 | KDM4E (0.74) | KDM4EPDE4BALDH1A1TSHRGAA | |
| SCHEMBL9305217 | 0.80 | KDM4E (0.74) | KDM4EPDE4BPOLBALDH1A1CYP2D6 | |
| SCHEMBL31737057 | 0.80 | KDM4E (0.74) | KDM4EPDE4BALDH1A1TSHRGAA | |
| SCHEMBL4534253 | 0.79 | KDM4E (0.42) | KDM4EPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1067955 | 0.79 | KDM4E (0.72) | KDM4EPDE4BPOLBALDH1A1CYP2D6 | |
| SCHEMBL680755 | 0.78 | KDM4E (0.71) | KDM4EPDE4BPOLBALDH1A1CYP2D6 | |
| SCHEMBL31737297 | 0.78 | KDM4E (0.71) | KDM4EPDE4BPOLBALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488569-B1 | A SILICONE COMPOUND | UNILEVER NV (NL) | 2015-01-07 | — | — | EP | disclosed |
| EP-2488569-A1 | A SILICONE COMPOUND | Unilever NV (NL) | 2012-08-22 | — | — | EP | disclosed |
| US-20120201765-A1 | SILICONE COMPOUND | UNILEVER NV (NL) | 2012-08-09 | — | — | US | disclosed |
| WO-2011045149-A1 | A SILICONE COMPOUND | UNILEVER NV (NL) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120201765-A1 | SILICONE COMPOUND | RAD51, ERCC1, CDH1 | KDM4E 165/4885PDE4B 4518/4885PDE4A 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.