SCHEMBL4534253

SCHEMBL4534253

C=CC(=O)CC(=O)C=C(c1ccc(OCCC[Si](OCC)(OCC)OCC)c(OC)c1)c1ccc(OCCC[Si](OCC)(OCC)OCC)c(OC)c1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 1/20 0.41
PDE4A P27815 1/20 0.40
PDE4B Q07343 1/20 0.40
PDE4C Q08493 1/20 0.40
PDE4D Q08499 1/20 0.40
SMPD1 P17405 4/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TP53 P04637 1/20 0.39
PRSS1 P07477 1/20 0.39
SLC6A5 Q9Y345 1/20 0.39
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28909246 0.82 NFE2L2 (0.56) KDM4ETSHRMAPK1MAPTLMNA
SCHEMBL1672224 0.79 KDM4E (0.63) KDM4ETSHRMAPK1MAPTPDE4A
SCHEMBL15209885 0.78 PDE4A (0.41) KDM4ETSHRMAPK1MAPTPDE4A
SCHEMBL30007299 0.75 NFE2L2 (0.62) KDM4ETSHRMAPK1MAPTLMNA
SCHEMBL498487 0.74 MEN1 (0.54) KDM4ETSHRMAPK1MAPTLMNA
SCHEMBL1761113 0.71 PTGES (0.53) KDM4EMAPTLMNA
SCHEMBL4826955 0.70 PDE4A (0.63) TSHRMAPK1PDE4APDE4BPDE4C
SCHEMBL4826967 0.70 PDE4A (0.63) TSHRMAPK1PDE4APDE4BPDE4C
SCHEMBL7552090 0.68 KDM4E (0.69) KDM4EMAPK1MAPTMEN1KMT2A
SCHEMBL7554736 0.68 KDM4E (0.69) KDM4EMAPK1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2638117-B1 SURFACE TREATMENT PROCESS, COMPOSITION FOR USE THEREIN, AND TREATED ARTICLE 3M INNOVATIVE PROPERTIES CO (US) 2015-09-23 EP disclosed
EP-2638117-A1 SURFACE TREATMENT PROCESS, COMPOSITION FOR USE THEREIN, AND TREATED ARTICLE 3M Innovative Properties Company (US) 2013-09-18 EP disclosed
US-20130220177-A1 SURFACE TREATMENT PROCESS, COMPOSITION FOR USE THEREIN, AND TREATED ARTICLE 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-08-29 US disclosed
WO-2012064653-A1 SURFACE TREATMENT PROCESS, COMPOSITION FOR USE THEREIN, AND TREATED ARTICLE 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-05-18 WO disclosed