Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445468 | 0.90 | ELANE (0.47) | ALDH1A1HBBHSD17B10ELANEKDM4E | |
| SCHEMBL13543201 | 0.87 | BCAT2 (0.59) | ALDH1A1KMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5058742 | 0.83 | ALDH1A1 (0.45) | ALDH1A1HBBHSD17B10ELANEKDM4E | |
| SCHEMBL5951641 | 0.82 | CYP2C19 (0.39) | ALDH1A1HBBHSD17B10ELANEKDM4E | |
| SCHEMBL17448835 | 0.82 | HCRTR2 (0.43) | KDM4EKMT2AMAPK1L3MBTL1 | |
| SCHEMBL12083366 | 0.81 | KDM4E (0.54) | ALDH1A1HSD17B10KDM4EALOX15KMT2A | |
| SCHEMBL5079740 | 0.81 | PDK2 (0.42) | ALDH1A1ELANEKDM4EALOX15KMT2A | |
| SCHEMBL16470694 | 0.81 | ELANE (0.41) | ALDH1A1HBBHSD17B10ELANEKDM4E | |
| SCHEMBL7949878 | 0.81 | HPGD (0.47) | ALDH1A1HSD17B10ELANEKDM4EKMT2A | |
| SCHEMBL5847579 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KDM4EALOX15KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593197-B2 | Trigger-responsive chain-shattering polymers | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-03-14 | — | — | US | disclosed |
| US-20150141453-A1 | Trigger-Responsive Chain-Shattering Polymers | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141453-A1 | Trigger-Responsive Chain-Shattering Polymers | SGTA, FUS, EWSR1 | ALDH1A1 4343/4885HBB 1099/4885HSD17B10 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.