Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445468 | 0.91 | ELANE (0.47) | ELANEALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL5058742 | 0.84 | ALDH1A1 (0.45) | ELANEALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL279655 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL16470694 | 0.82 | ELANE (0.41) | ELANEALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL5847579 | 0.82 | ALDH1A1 (0.64) | ALDH1A1KDM4ESMN1; SMN2MAPTKMT2A | |
| SCHEMBL16722809 | 0.81 | ALDH1A1 (0.47) | ELANEALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL6375203 | 0.81 | PDK2 (0.40) | PDK2PDK1PDK3PDK4ELANE | |
| SCHEMBL6604550 | 0.80 | CES1 (0.50) | PDK2PDK1PDK3PDK4ALDH1A1 | |
| SCHEMBL7596837 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL11373632 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-20230034284-A1 | FUNCTIONALIZED N-ACETYLGALACTOSAMINE NUCLEOSIDES | HONGENE BIOTECH CORPORATION | 2023-02-02 | — | — | US | disclosed |
| US-20210371579-A1 | VEGETABLE OIL-DERIVED EPOXY COMPOSITIONS HAVING IMPROVED PERFORMANCE | WASHINGTON STATE UNIVERSITY | 2021-12-02 | — | — | US | disclosed |
| US-20210154307-A1 | CATIONIC NANOSTRUCTURES FOR INTRA-CARTILAGE DELIVERY OF THERAPEUTICS AND CONTRAST AGENTS | NORTHEASTERN UNIVERSITY | 2021-05-27 | — | — | US | disclosed |
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |
| US-20090076032-A1 | Derivatives of 18Beta-Glycyrrhetinic Acid | VAMPEX LIMITED (GB) | 2009-03-19 | — | — | US | disclosed |
| US-7405252-B2 | Vinyl chloride resin composition | ADEKA CORPORATION (JP) | 2008-07-29 | — | — | US | disclosed |
| US-20070100049-A1 | Vinyl Chlodride Resin Composition | ADEKA CORPORATION (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1693414-A1 | VINYL CHLORIDE RESIN COMPOSITION | Asahi Denka Co., Ltd. (JP) | 2006-08-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | TRIM33, TRIM28, TRIM4 | PDK2 3493/4885PDK1 1864/4885PDK3 2886/4885 |
| US-20090076032-A1 | Derivatives of 18Beta-Glycyrrhetinic Acid | ALDH1A2, HSD17B1, ADH1B | PDK2 612/4885PDK1 496/4885PDK3 907/4885 |
| US-20210154307-A1 | CATIONIC NANOSTRUCTURES FOR INTRA-CARTILAGE DELIVERY OF THERAPEUTICS AND CONTRAST AGENTS | MMP1, MATR3, TIMP3 | PDK2 4466/4885PDK1 2450/4885PDK3 3409/4885 |
| US-20230034284-A1 | FUNCTIONALIZED N-ACETYLGALACTOSAMINE NUCLEOSIDES | FUT6, B3GNT2, GALNT6 | PDK2 2278/4885PDK1 2979/4885PDK3 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.