Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211170 | 0.91 | CA2 (0.57) | CA2CA12CA1CA7CA9 | |
| SCHEMBL22498547 | 0.85 | CA2 (0.55) | CA2CA12CA1CA7CA9 | |
| SCHEMBL8337382 | 0.85 | CA12 (0.59) | CA2CA12CA1CA7CA9 | |
| SCHEMBL9211531 | 0.83 | CA2 (0.57) | CA2CA12CA1CA7CA9 | |
| SCHEMBL4392307 | 0.81 | CA2 (0.55) | CA2CA12CA1CA7CA9 | |
| SCHEMBL15450963 | 0.81 | CA2 (0.59) | CA2CA12CA1CA7CA9 | |
| SCHEMBL23369402 | 0.81 | KDM4E (0.47) | CA2CA12CA1CA7CA9 | |
| SCHEMBL7392269 | 0.80 | CA12 (0.53) | CA2CA12CA1CA7CA9 | |
| SCHEMBL16314448 | 0.80 | THRA (0.56) | CA2CA12CA1CA7CA9 | |
| SCHEMBL28900582 | 0.80 | CA2 (0.53) | CA2CA12CA1CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044208-A1 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | THE UNIVERSITY OF MANCHESTER (GB) | 2017-02-16 | — | — | US | disclosed |
| US-20170044208-A1 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | THE UNIVERSITY OF MANCHESTER (GB) | 2017-02-16 | — | — | US | disclosed |
| WO-2015071657-A9 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | THE UNIVERSITY OF MANCHESTER (GB) | 2016-09-15 | — | — | WO | disclosed |
| WO-2015071657-A1 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | THE UNIVERSITY OF MANCHESTER (GB) | 2015-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044208-A1 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | NR3C1, NR3C2, NR5A1 | CA2 4260/4885CA12 4248/4885CA1 3421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.