Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471742 | 1.00 | MEN1 (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7776950 | 1.00 | MEN1 (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL27702986 | 1.00 | MEN1 (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL3390208 | 0.84 | RECQL (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL30893951 | 0.82 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL1061794 | 0.81 | LMNA (0.49) | KMT2AALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL11249889 | 0.81 | LMNA (0.49) | KMT2AALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL2968427 | 0.81 | LMNA (0.49) | KMT2AALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL6659711 | 0.81 | KDM4E (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL5170037 | 0.81 | KDM4E (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040482-B2 | Octapeptide compounds and therapeutic use thereof | IPSEN PHARMA S.A.S. (FR) | 2015-05-26 | — | — | US | disclosed |