SCHEMBL167301

SCHEMBL167301

C=CCOC(=O)CC(O)C(=O)OCC=C

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
TSHR P16473 2/20 0.43
CYP3A4 P08684 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
PKM P14618 1/20 0.36
MAPT P10636 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34
HSD17B10 Q99714 1/20 0.33
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
EPHX2 P34913 1/20 0.30
CASP1 P29466 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2348594 0.89 TSHR (0.46) TDP1TSHRCYP3A4NPSR1SMN1; SMN2
SCHEMBL7773895 0.88 TDP1 (0.38) TDP1TSHRCYP3A4NPSR1SMN1; SMN2
Methacrylic Acid SCHEMBL6558919 0.88 TDP1 (0.40) TDP1TSHRCYP3A4NPSR1SMN1; SMN2
SCHEMBL23781344 0.86 TDP1 (0.40) TDP1TSHRCYP3A4NPSR1SMN1; SMN2
SCHEMBL7394257 0.86 TDP1 (0.40) TDP1TSHRCYP3A4NPSR1SMN1; SMN2
SCHEMBL829459 0.86 SMN1; SMN2 (0.43) TDP1TSHRCYP3A4NPSR1SMN1; SMN2
SCHEMBL7395772 0.85 TDP1 (0.42) TDP1TSHRCYP3A4NPSR1MAPT
SCHEMBL367991 0.83 SMN1; SMN2 (0.44) TDP1TSHRCYP3A4SMN1; SMN2MAPT
SCHEMBL7489183 0.83 SMN1; SMN2 (0.44) TDP1TSHRCYP3A4SMN1; SMN2MAPT
SCHEMBL3688622 0.83 TSHR (0.53) TDP1TSHRNPSR1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1616 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115700266-B Packaging adhesive film 万华化学集团股份有限公司 2024-06-25 CN claimed
US-20240074956-A1 COSMETIC COMPOSITIONS, KITS THEREOF, AND METHODS FOR MAKING AND USING THE SAME L'OREAL (FR) 2024-03-07 US claimed
US-11819560-B2 Cosmetic compositions, kits thereof, and methods for making and using the same L'OREAL (FR) 2023-11-21 US claimed
WO-2023164280-A1 COMPOSITIONS AND METHODS FOR CURLY HAIR RUGHANI RONAK (US) 2023-08-31 WO claimed
CN-116635001-A Composition for caring for and/or making up keratin materials 莱雅公司 2023-08-22 CN claimed
EP-4203904-A1 COSMETIC COMPOSITIONS, KITS THEREOF, AND METHODS FOR MAKING AND USING THE SAME L'OREAL (FR) 2023-07-05 EP claimed
WO-2023078367-A1 SECONDARY BATTERY 珠海冠宇电池股份有限公司 2023-05-11 WO claimed
WO-2023055751-A1 MIXED SOLVENT HYDROGEL SYSTEM FOR WOUND HEALING UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-04-06 WO claimed
CN-113563840-B Ultraviolet curing display screen side sealing adhesive and preparation method thereof 广东恒大新材料科技有限公司 2023-03-10 CN claimed
CN-115700266-A Packaging adhesive film 万华化学集团股份有限公司 2023-02-07 CN claimed
EP-0271992-B1 MACHINE DISHWASHING COMPOSITION UNILEVER PLC (GB) 1991-12-18 EP claimed
EP-0403605-A4 ELASTASE INHIBITING POLYMERS AND METHODS UNIV KENTUCKY RES FOUND (US) 1991-08-21 EP claimed
EP-0403605-A1 ELASTASE INHIBITING POLYMERS AND METHODS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1990-12-27 EP claimed
EP-0368449-A2 Elastase inhibiting polymers and methods to produce them Digenis, George Alexander (US) 1990-05-16 EP claimed
WO-1990002558-A1 ELASTASE INHIBITING POLYMERS AND METHODS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1990-03-22 WO claimed
US-4863632-A BROMO OR CHLORO COMPOUND CORE, POLYMER COATING LEVER BROTHERS COMPANY (US) 1989-09-05 US claimed
EP-0271992-A2 Machine dishwashing composition UNILEVER PLC (GB) 1988-06-22 EP claimed
US-4608411-A COPOLYMERS OF UNSATURATED ALKYL ESTERS BASED ON LONG CHAIN FATTY AALCOHOL; CRYSTAL GROWTH INHIBITORS SOCIETE NATIONALE ELF AQUITAINE (FR) 1986-08-26 US claimed
US-4280888-A ALLYL POLYENES CROSSLINKED WITH A POLYTHIOL COMPOUND W. R. GRACE & CO. (US) 1981-07-28 US claimed
US-4113442-A C 10-40 HYDROCARBYL ESTER OF HYDROXYCARBOXYLIC ACID AS FILTERABILITY IMPROBER SHELL OIL COMPANY (US) 1978-09-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074956-A1 COSMETIC COMPOSITIONS, KITS THEREOF, AND METHODS FOR MAKING AND USING THE SAME CUTA, LIPC, MGLL TDP1 2265/4885TSHR 4421/4885CYP3A4 4311/4885
US-11819560-B2 Cosmetic compositions, kits thereof, and methods for making and using the same CUTA, LIPC, MGLL TDP1 2265/4885TSHR 4421/4885CYP3A4 4311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.