SCHEMBL1673103

SCHEMBL1673103

CC(CBr)C(=O)OCCO

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
ALDH1A1 P00352 3/20 0.36
ACHE P22303 1/20 0.34
CHRNB2 P17787 2/20 0.31
CHRNB4 P30926 2/20 0.31
CHRNA3 P32297 2/20 0.31
CHRNA4 P43681 2/20 0.31
CYP2C19 P33261 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4144141 0.88 ALDH1A1 (0.33) TSHRALDH1A1CHRNB2CHRNB4CHRNA3
SCHEMBL15380000 0.84 FAAH (0.37) TSHRALDH1A1ACHE
SCHEMBL786190 0.79 ACHE (0.39) TSHRALDH1A1ACHECHRNB2CHRNB4
SCHEMBL13876695 0.79 ACHE (0.39) TSHRALDH1A1ACHECHRNB2CHRNB4
SCHEMBL15521662 0.79 ACHE (0.39) TSHRALDH1A1ACHECHRNB2CHRNB4
SCHEMBL12893358 0.79 TSHR (0.38) TSHRALDH1A1ACHECHRNB2CHRNB4
SCHEMBL20515383 0.78 TSHR (0.34) TSHRALDH1A1ACHE
SCHEMBL21733115 0.77 TSHR (0.37) TSHRALDH1A1ACHECHRNB2CHRNB4
SCHEMBL17365966 0.77 TSHR (0.37) TSHRALDH1A1ACHECHRNB2CHRNB4
SCHEMBL20448324 0.77 TSHR (0.37) TSHRALDH1A1ACHECHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115161011-B High-stability perovskite phase CsPbI 3 Nanocrystalline and preparation method thereof 上海电力大学 2024-03-01 CN claimed
CN-115161011-A High-stability perovskite phase CsPbI 3 Nanocrystalline and preparation method thereof 上海电力大学 2022-10-11 CN claimed
CN-115161011-B High-stability perovskite phase CsPbI 3 Nanocrystalline and preparation method thereof 上海电力大学 2024-03-01 CN disclosed
CN-115161011-A High-stability perovskite phase CsPbI 3 Nanocrystalline and preparation method thereof 上海电力大学 2022-10-11 CN disclosed
CN-114773202-A Preparation method and application of probe for analyzing influence of interpenetrating network topology structure on material performance 电子科技大学长三角研究院(湖州) 2022-07-22 CN disclosed
US-20210208140-A1 DIAGNOSTIC METHODS FOR THE DETECTION AND QUANTIFICATION OF BLOOD-RELATED DISEASES ADOLPHE MERKLE INSTITUTE, UNIVERSITY OF FRIBOURG (CH) 2021-07-08 US disclosed
EP-3458859-B1 DIAGNOSTIC METHODS FOR THE DETECTION AND QUANTIFICATION OF BLOOD-RELATED DISEASES ADOLPHE MERKLE INSTITUTE UNIV OF FRIBOURG (CH) 2021-07-07 EP disclosed
CN-107573445-B Polymer backbone element tag 富鲁达加拿大公司 2021-05-25 CN disclosed
US-10983122-B2 Diagnostic methods for the detection and quantification of blood-related diseases ADOLPHE MERKLE INSTITUTE, UNIVERSITY OF FRIBOURG (CH) 2021-04-20 US disclosed
CN-107076741-B Polymer microparticles for loading physiologically active substance and process for producing the same 美迪恩斯生命科技株式会社 2020-11-24 CN disclosed
US-20190160007-A1 Integrated Nano System for Liver-Targeting Co-Delivery of Genes/Drugs and Preparation Method JIANGNAN UNIVERSITY (CN) 2019-05-30 US disclosed
US-20090198327-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON INC. (CH) 2009-08-06 US disclosed
US-20090093604-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON, INC. (CH) 2009-04-09 US disclosed
WO-2009046235-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON, INC. (CH) 2009-04-09 WO disclosed
EP-1891127-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON INC. (CH) 2008-02-27 EP disclosed
EP-1891466-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON INC. (CH) 2008-02-27 EP disclosed
WO-2006138188-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON, INC. (CH) 2006-12-28 WO disclosed
WO-2006138213-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON, INC. (CH) 2006-12-28 WO disclosed
US-20060282163-A1 Ophthalmic and otorhinolaryngological device materials ALCON, INC. 2006-12-14 US disclosed
US-20060281888-A1 Ophthalmic and otorhinolaryngological device materials ALCON, INC. 2006-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190160007-A1 Integrated Nano System for Liver-Targeting Co-Delivery of Genes/Drugs and Preparation Method GUSB, GDA, GLA TSHR 2848/4885ALDH1A1 573/4885ACHE 2513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.