Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Aniline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL676147 | 0.89 | TSHR (0.65) | TSHRALDH1A1NT5EKEAP1KMT2A | |
| Aniline SCHEMBL167326 | 0.89 | TSHR (0.65) | TSHRALDH1A1NT5EKEAP1KMT2A | |
| Aniline SCHEMBL167327 | 0.89 | TSHR (0.65) | TSHRALDH1A1NT5EKEAP1KMT2A | |
| Aniline SCHEMBL5693986 | 0.86 | TSHR (0.61) | TSHRALDH1A1NT5EKEAP1KMT2A | |
| Aniline SCHEMBL28037884 | 0.86 | TSHR (0.61) | TSHRALDH1A1NT5EKEAP1KMT2A | |
| Aniline SCHEMBL3156113 | 0.86 | TSHR (0.61) | TSHRALDH1A1NT5EKEAP1KMT2A | |
| SCHEMBL4591174 | 0.86 | TSHR (0.62) | TSHRALDH1A1NT5EKMT2ATDP1 | |
| Aniline SCHEMBL7863425 | 0.85 | TSHR (0.52) | TSHRALDH1A1NT5EKEAP1KMT2A | |
| Aniline SCHEMBL8022436 | 0.85 | TSHR (0.52) | TSHRALDH1A1NT5EKEAP1KMT2A | |
| Aniline SCHEMBL10806060 | 0.85 | TSHR (0.52) | TSHRALDH1A1NT5EKEAP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119614413-A | Lactobacillus bread, high-density culture method and application thereof | 华南理工大学 | 2025-03-14 | — | — | CN | disclosed |
| CN-115491329-B | Breast milk source lactobacillus plantarum HM-P2 and application thereof | 北京三元食品股份有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-113924085-A | Compositions and methods for increasing muscle mass and oxidative metabolism | 加利福尼亚大学董事会 | 2022-01-11 | — | — | CN | disclosed |
| CN-110628663-B | Lactobacillus rhamnosus and high-density culture method and application thereof | 华南理工大学 | 2021-12-17 | — | — | CN | disclosed |
| CN-110628663-A | Lactobacillus rhamnosus and high-density culture method and application thereof | 华南理工大学 | 2019-12-31 | — | — | CN | disclosed |
| US-8476369-B2 | Metal salt nanogel-containing polymers | BAYER INNOVATION GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| US-20100178270-A1 | METAL SALT NANOGEL-CONTAINING POLYMERS | HELLING INNOVATION UG | 2010-07-15 | — | — | US | disclosed |
| US-20090076019-A1 | METHODS FOR TREATING NEUROLOGICAL DISORDERS OR DAMAGE | MOUNT SINAI HOSPITAL (CA) | 2009-03-19 | — | — | US | disclosed |
| WO-2008043853-A2 | PHOTOCHROMIC FILM | OPCO GMBH (DE) | 2008-04-17 | — | — | WO | disclosed |
| US-20080075686-A1 | Deodorizer and method for using the same | TOTO LTD. (JP) | 2008-03-27 | — | — | US | disclosed |
| US-4310449-A | Process for the preparation of stable dispersions | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-12 | — | — | US | disclosed |
| US-4310448-A | POLYETHER OR POLYESTER DISPERSANTS FOR POLYURETHANES OR POLUREAS | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-12 | — | — | US | disclosed |
| US-4305858-A | Process for the preparation of stable ionic dispersions of polyisocyanate-polyaddition products in hydroxyl containing compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-15 | — | — | US | disclosed |
| US-4184990-A | Process for the preparation of stable dispersions of polyisocyanate-polyaddition products in a hydroxyl containing compound as dispersing agent | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | disclosed |
| US-4147680-A | Production of polyurethane resins using as active hydrogen material a stable dispersion of ionic polyisocyanate-polyaddition products in hydroxyl containing compounds as a dispersing agent | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-03 | — | — | US | disclosed |
| US-4142030-A | POLYURETHANE-SILICATE | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-27 | — | — | US | disclosed |
| US-4042536-A | POLYISOCYANATE, SILICIC ACID, XEROGEL | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-16 | — | — | US | disclosed |
| US-4008066-A | Phenylaminoacetamides for regulating plant growth | CIBA-GEIGY CORPORATION (US) | 1977-02-15 | — | — | US | disclosed |
| US-3988268-A | Polyurethane foam plastics which contain ionic groups | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-26 | — | — | US | disclosed |
| US-3970601-A | COATINGS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100178270-A1 | METAL SALT NANOGEL-CONTAINING POLYMERS | PUF60, WASHC5, SLC39A3 | TSHR 4678/4885ALDH1A1 2297/4885NT5E 4244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.