Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2144304 | 0.88 | EGLN1 (0.60) | EGLN1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL2144302 | 0.86 | EGLN1 (0.75) | EGLN1MAPTLMNAL3MBTL1HPGD | |
| SCHEMBL2353779 | 0.81 | EGLN1 (0.60) | EGLN1MAPTLMNAPOLBKMT2A | |
| SCHEMBL16735597 | 0.81 | EGLN1 (0.77) | EGLN1MAPTLMNAPOLB | |
| SCHEMBL2296475 | 0.80 | EGLN1 (0.53) | EGLN1MAPTL3MBTL1HPGDKMT2A | |
| SCHEMBL2291211 | 0.77 | EGLN1 (0.76) | EGLN1KMT2A | |
| SCHEMBL16735617 | 0.76 | EGLN1 (0.58) | EGLN1L3MBTL1RXFP1TP53KMT2A | |
| SCHEMBL2294722 | 0.76 | HPGD (0.59) | EGLN1MAPTLMNAPOLBTP53 | |
| SCHEMBL617738 | 0.75 | MAPT (0.52) | EGLN1MAPTLMNAPOLBTHRB | |
| SCHEMBL2201947 | 0.75 | EGLN1 (0.79) | EGLN1MAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |