Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2144302 | 0.83 | EGLN1 (0.75) | EGLN1ADORA2AADORA1KMT2AL3MBTL1 | |
| SCHEMBL2144304 | 0.83 | EGLN1 (0.60) | EGLN1KMT2AL3MBTL1HPGDMAPT | |
| SCHEMBL16735679 | 0.80 | EGLN1 (0.57) | EGLN1ADORA2AADORA1KMT2AL3MBTL1 | |
| SCHEMBL16735597 | 0.78 | EGLN1 (0.77) | EGLN1ALDH1A1TSHRMAPT | |
| SCHEMBL2353779 | 0.78 | EGLN1 (0.60) | EGLN1KMT2AMAPT | |
| SCHEMBL2294722 | 0.77 | HPGD (0.59) | EGLN1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2291211 | 0.77 | EGLN1 (0.76) | EGLN1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL16735665 | 0.76 | EGLN1 (0.74) | EGLN1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL16735617 | 0.75 | EGLN1 (0.58) | EGLN1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2206161 | 0.75 | EGLN1 (0.73) | EGLN1ADORA2AADORA1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |
| EP-2519505-A1 | NEW TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | Polichem SA (LU) | 2012-11-07 | — | — | EP | claimed |
| WO-2011080264-A1 | NEW TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM S.A. (LU) | 2011-07-07 | — | — | WO | claimed |