Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2144302 | 0.89 | EGLN1 (0.75) | EGLN1MAPTLMNAKMT2AHPGD | |
| SCHEMBL2353779 | 0.88 | EGLN1 (0.60) | EGLN1MAPTLMNAPOLBKMT2A | |
| SCHEMBL16735597 | 0.88 | EGLN1 (0.77) | EGLN1MAPTLMNAPOLB | |
| SCHEMBL16735679 | 0.88 | EGLN1 (0.57) | EGLN1MAPTLMNAPOLBHDAC6 | |
| SCHEMBL2201947 | 0.87 | EGLN1 (0.79) | EGLN1MAPTLMNAPOLB | |
| SCHEMBL16735617 | 0.83 | EGLN1 (0.58) | EGLN1TDP1KMT2AL3MBTL1 | |
| SCHEMBL2296475 | 0.83 | EGLN1 (0.53) | EGLN1MAPTKMT2AHPGDL3MBTL1 | |
| SCHEMBL2294722 | 0.78 | HPGD (0.59) | EGLN1MAPTLMNAPOLBTDP1 | |
| SCHEMBL2291211 | 0.78 | EGLN1 (0.76) | EGLN1KMT2A | |
| SCHEMBL7688599 | 0.75 | EGLN1 (0.80) | EGLN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |
| EP-2345643-A1 | New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof | POLICHEM S.A. (LU) | 2011-07-20 | — | — | EP | disclosed |