SCHEMBL16738293

SCHEMBL16738293

CC[Al](CC)Oc1ccccc1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 4/20 0.47
HTR7 P34969 1/20 0.46
MAPK1 P28482 2/20 0.44
TP53 P04637 1/20 0.44
RAB9A P51151 1/20 0.44
ADRB1 P08588 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 6/20 0.41
ALDH1A1 P00352 2/20 0.41
NCOA1 Q15788 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LMNA P02545 2/20 0.40
HRH1 P35367 1/20 0.39
PKM P14618 1/20 0.38
KMT2A Q03164 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3698066 0.81 PDCD1 (0.39) ADRB2HTR7MAPK1TP53RAB9A
SCHEMBL11116087 0.80 HTR7 (0.42) ADRB2HTR7MAPK1TP53RAB9A
SCHEMBL16738296 0.77 MAPK1 (0.47) ADRB2HTR7MAPK1TP53RAB9A
SCHEMBL112422 0.74 NCOA1 (0.63) ADRB2HTR7MAPK1TP53RAB9A
SCHEMBL203121 0.74 ADRB2 (0.61) ADRB2HTR7MAPK1TP53RAB9A
SCHEMBL11197784 0.73 HTR7 (0.42) ADRB2HTR7MAPK1TP53RAB9A
Propane SCHEMBL27542299 0.72 ADRB2 (0.59) ADRB2HTR7MAPK1TP53RAB9A
Fluoride SCHEMBL27432507 0.72 ADRB2 (0.59) ADRB2HTR7MAPK1TP53RAB9A
SCHEMBL10756496 0.72 NCOA1 (0.61) ADRB2HTR7MAPK1TP53RAB9A
SCHEMBL28431579 0.72 NCOA1 (0.61) ADRB2HTR7MAPK1TP53RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9487604-B2 Bimetallic cobalt-aluminum adduct catalyst system for preparing high trans-1,4-polybutadiene KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-11-08 US disclosed
US-20150148503-A1 NOVEL BIMETALLIC COBALT-ALUMINUM ADDUCT CATALYST SYSTEM FOR PREPARING HIGH TRANS-1,4-POLYBUTADIENE KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2015-05-28 US disclosed