Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197784 | 0.86 | HTR7 (0.42) | HTR7ADRB2MAPK1TP53RAB9A | |
| SCHEMBL1561072 | 0.83 | ADRA2A (0.38) | HTR7ADRB2MAPK1USP2LMNA | |
| SCHEMBL16738293 | 0.80 | ADRB2 (0.47) | HTR7ADRB2MAPK1TP53RAB9A | |
| SCHEMBL28665971 | 0.77 | CYP1A2 (0.40) | ADRB2TP53RAB9ALMNAKDM4E | |
| SCHEMBL7002818 | 0.74 | ADRB2 (0.36) | HTR7ADRB2MAPK1TP53RAB9A | |
| SCHEMBL1561473 | 0.74 | LMNA (0.41) | ADRB2LMNAMAPTALDH1A1ADRB1 | |
| SCHEMBL16738296 | 0.73 | MAPK1 (0.47) | HTR7ADRB2MAPK1TP53RAB9A | |
| SCHEMBL15094850 | 0.73 | ADRB2 (0.55) | HTR7ADRB2MAPK1TP53RAB9A | |
| SCHEMBL7735423 | 0.72 | ADRA2A (0.38) | HTR7ADRB2MAPK1USP2LMNA | |
| SCHEMBL28652108 | 0.72 | HTR1B (0.46) | ADRB2MAPK1TP53LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043125-B1 | ALUMINIUM-ORGANIC COMPOUNDS, PREPARATION OF THESE COMPOUNDS, COSMETIC COMPOSITIONS CONTAINING THESE COMPOUNDS AS ACTIVE AGENTS AND USE OF THESE COMPOSITIONS TO COMBAT AND PREVENT SEBORRHOEA | Richardson-Vicks, Inc. (US) | 1984-11-28 | — | — | EP | disclosed |
| US-4421749-A | ANTI-DANDRUFF | HOFFMANN-LA ROCHE INC. (US) | 1983-12-20 | — | — | US | disclosed |
| EP-0043125-A2 | Aluminium-organic compounds, preparation of these compounds, cosmetic compositions containing these compounds as active agents and use of these compositions to combat and prevent seborrhoea | Richardson-Vicks, Inc. (US) | 1982-01-06 | — | — | EP | disclosed |