Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840488 | 0.90 | GAA (0.46) | GAAMCOLN3HDAC9KDM1AHTR2A | |
| SCHEMBL18049075 | 0.75 | TSHR (0.40) | HDAC9HCAR2KDM1AMAOBTSHR | |
| SCHEMBL3840701 | 0.71 | HTR6 (0.40) | GAAMCOLN3HTR2AHTR2CHTR2B | |
| SCHEMBL3841136 | 0.71 | GAA (0.46) | GAAMCOLN3KDM1ATSHRHTR2A | |
| SCHEMBL315173 | 0.71 | GAA (0.42) | GAAMCOLN3HDAC9KDM1A | |
| SCHEMBL315669 | 0.71 | GAA (0.42) | GAAMCOLN3HDAC9KDM1A | |
| SCHEMBL315773 | 0.71 | GAA (0.39) | GAAMCOLN3HDAC9KDM1AMAOB | |
| Benzene SCHEMBL11415270 | 0.70 | KDM1A (0.47) | HDAC9HCAR2KDM1AMAOBTSHR | |
| SCHEMBL29832096 | 0.70 | GAA (0.57) | GAAMCOLN3TSHRTDP1RORC | |
| SCHEMBL3854188 | 0.69 | HDAC9 (0.39) | GAAMCOLN3HDAC9HCAR2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074375-B1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INT (DE) | 2018-04-04 | — | — | EP | disclosed |
| EP-3074375-A1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | Boehringer Ingelheim International GmbH (DE) | 2016-10-05 | — | — | EP | disclosed |
| US-9308194-B2 | Indanyloxyphenylcyclopropanecarboxylic acids | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| WO-2015078802-A1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-06-04 | — | — | WO | disclosed |
| US-20150148347-A1 | INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148347-A1 | INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | GPR119, INSR, GPR65 | GAA 4157/4885MCOLN3 1145/4885HDAC9 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.