Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPRF | P10586 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191410 | 0.72 | BACE1 (0.44) | BACE1MAOAMAOBSIGMAR1DRD2 | |
| SCHEMBL28862246 | 0.70 | BACE1 (0.41) | BACE1MAOAMAOBPTPN1PTPRC | |
| SCHEMBL9763216 | 0.68 | BACE1 (0.38) | BACE1MAOAMAOBPTPN1PTPRC | |
| SCHEMBL12814848 | 0.65 | CYP2B6 (0.35) | — | |
| SCHEMBL29035103 | 0.64 | BACE1 (0.45) | BACE1MAOAMAOBPTPN1PTPRC | |
| SCHEMBL6253344 | 0.63 | TAAR1 (0.37) | MAOAMAOBSIGMAR1TP53RAB9A | |
| SCHEMBL4811799 | 0.63 | — | — | |
| SCHEMBL668518 | 0.62 | BACE1 (0.39) | BACE1MAOAMAOBSIGMAR1DRD2 | |
| SCHEMBL28873124 | 0.62 | PTPN1 (0.47) | BACE1MAOAMAOBPTPN1PTPRC | |
| SCHEMBL6252469 | 0.62 | HPGD (0.33) | HPGDSMN1; SMN2L3MBTL1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521125-B1 | Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound | RICOH CO LTD (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-7309552-B2 | Containing the reaction product of a dibenzo [a,c]phenadine-2,7-bisdiazonium salt and a coupler such as N-benzyl-2-hydroxy-7,8-naphthalic acid imide; stilbene charge transport material; 1alkylidene-2,3-diphenylindene acceptor; biphenol; copolycarbonate containing arylamine groups; highly durable | RICOH COMPANY, LTD. (JP) | 2007-12-18 | — | — | US | disclosed |
| US-20050266331-A1 | Electrophotographic photoconductor, electrophotography, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound | RICOH COMPANY, LTD. (JP) | 2005-12-01 | — | — | US | disclosed |
| EP-1521125-A1 | Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound | Ricoh Company (JP) | 2005-04-06 | — | — | EP | disclosed |