Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664820 | 0.69 | TRPA1 (0.45) | NPC1RAB9AKDM4EPAX8L3MBTL1 | |
| SCHEMBL30449712 | 0.68 | SPR (0.59) | NPC1RAB9AKDM4EPAX8MAPT | |
| SCHEMBL1193113 | 0.68 | SPR (0.59) | NPC1RAB9AKDM4EPAX8MAPT | |
| SCHEMBL6281434 | 0.68 | AURKA (0.55) | NPC1RAB9AKDM4EPAX8EGLN1 | |
| SCHEMBL5252860 | 0.68 | CHEK1 (0.53) | NPC1RAB9AKDM4EMAPTTP53 | |
| SCHEMBL15246754 | 0.68 | RAB9A (0.61) | NPC1RAB9AKDM4EPAX8MAPT | |
| SCHEMBL12748139 | 0.68 | NPC1 (0.51) | NPC1RAB9AKDM4EPAX8MAPT | |
| SCHEMBL7068732 | 0.67 | ERCC1 (0.54) | KHKIRAK4NR3C1 | |
| SCHEMBL2252555 | 0.65 | NPC1 (0.92) | NPC1RAB9AKDM4EMAPTTP53 | |
| SCHEMBL17470481 | 0.64 | NPC1 (0.76) | NPC1RAB9AKDM4EMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015075051-A1 | ALLOSTERIC INHIBITORS OF ATYPICAL PROTEIN KINASES C | UNIVERSITAET DES SAARLANDES (DE) | 2015-05-28 | — | — | WO | disclosed |