Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.76 |
| ▸ | RAB9A | P51151 | 9/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.71 |
| ▸ | HPGD | P15428 | 5/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.71 |
| ▸ | TP53 | P04637 | 3/20 | 0.71 |
| ▸ | PKM | P14618 | 3/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.59 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417301 | 0.94 | NPC1 (0.78) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL28027557 | 0.93 | KDM4E (0.75) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL12887920 | 0.91 | NPC1 (0.63) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL31592975 | 0.88 | MMP2 (0.64) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL2252555 | 0.87 | NPC1 (0.92) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| Benzene SCHEMBL28005151 | 0.87 | NPC1 (1.00) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL105095 | 0.87 | NPC1 (1.00) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL12153689 | 0.87 | NPC1 (0.77) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| SCHEMBL23132010 | 0.85 | SMN1; SMN2 (0.61) | NPC1RAB9AGAASMN1; SMN2KDM4E | |
| Potassium SCHEMBL4891434 | 0.85 | NPC1 (0.96) | NPC1RAB9AGAASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022117473-A1 | HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-06-09 | — | — | WO | disclosed |
| EP-3172775-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-04-20 | — | — | EP | disclosed |
| US-20170222157-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-08-03 | — | — | US | disclosed |
| US-20170222157-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-08-03 | — | — | US | disclosed |
| WO-2016012075-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170222157-A1 | MATERIALS FOR ELECTRONIC DEVICES | EYA3, EYA2, MITF | NPC1 2290/4885RAB9A 1446/4885GAA 3195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.