SCHEMBL1674191

SCHEMBL1674191

Cc1ccc(NC=O)c(O)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 2/20 0.41
ESR2 Q92731 1/20 0.40
POLB P06746 1/20 0.34
RECQL P46063 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PABPC1 P11940 1/20 0.33
ALDH1A1 P00352 3/20 0.31
TRPA1 O75762 1/20 0.31
ATM Q13315 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 2/20 0.31
LMNA P02545 2/20 0.30
HTT P42858 2/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5609677 0.81 KDM5A (0.40) KDM5AESR2NPSR1TDP1PABPC1
SCHEMBL13412750 0.76 ALDH1A1 (0.50) KDM5ATDP1PABPC1ALDH1A1TRPA1
SCHEMBL17998045 0.74 IDO1 (0.39) POLBRECQLNPSR1TDP1ALDH1A1
SCHEMBL5610330 0.72 KDM5A (0.48) KDM5AESR2POLBTDP1PABPC1
SCHEMBL5464068 0.72 CYP3A4 (0.53) KDM5APOLBRECQLTDP1ALDH1A1
SCHEMBL11207914 0.72 TSHR (0.44) KDM5AESR2RECQLTDP1PABPC1
SCHEMBL5857982 0.71 KDM5A (0.43) KDM5AESR2PABPC1ALDH1A1TSHR
SCHEMBL4776892 0.71 KEAP1 (0.52) POLBTDP1ALDH1A1TRPA1ATM
SCHEMBL28244310 0.71 ESR2 (0.37) KDM5AESR2PABPC1HTT
SCHEMBL27565722 0.71 ESR2 (0.37) KDM5AESR2RECQLTDP1PABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1979086-B1 FLOW-TYPE LABORATORY OZONOLYSIS APPARATUS AND METHOD OF PERFORMING OZONOLYSIS REACTION THALESNANO NANOTECHNOLOGIAI ZRT (HU) 2011-11-02 EP disclosed
US-7919055-B2 Method of forming a sealed channel of a microfluidic reactor and a microfluidic reactor comprising such channel ThalesNano Nanotechnológiai Zrt. (HU) 2011-04-05 US disclosed
US-7687229-B2 Silver halide color photographic light-sensitive material and image forming method FUJIFILM CORPORATION (JP) 2010-03-30 US disclosed
US-20090101519-A1 FLOW-TYPE LABORATORY OZONOLYSIS APPARATUS AND METHOD OF PERFORMING OZONOLYSIS REACTION THALESNANO NANOTECHNOLOGIAI ZRT. (HU) 2009-04-23 US disclosed
US-20090098029-A1 METHOD OF FORMING A SEALED CHANNEL OF A MICROFLUIDIC REACTOR AND A MICROFLUIDIC REACTOR COMPRISING SUCH CHANNEL THALESNANO NANOTECHNOLOGIAI ZRT. (HU) 2009-04-16 US disclosed
EP-1979086-A2 FLOW-TYPE LABORATORY OZONOLYSIS APPARATUS AND METHOD OF PERFORMING OZONOLYSIS REACTION Thalesnano Nanotechnológiai Zrt. (HU) 2008-10-15 EP disclosed
EP-1971548-A2 METHOD OF FORMING A SEALED CHANNEL OF A MICROFLUIDIC REACTOR AND A MICROFLUIDIC REACTOR COMPRISING SUCH CHANNEL Thalesnano Nanotechnológiai Zrt. (HU) 2008-09-24 EP disclosed
US-20070298348-A1 Silver Halide Color Photographic Light-Sensitive Material and Image Forming Method FUJIFILM CORPORATION (JP) 2007-12-27 US disclosed
WO-2007072097-A2 FLOW-TYPE LABORATORY OZONOLYSIS APPARATUS AND METHOD OF PERFORMING OZONOLYSIS REACTION ThalesNano Nanotechnológiai Zrt. (HU) 2007-06-28 WO disclosed
WO-2007072099-A2 METHOD OF FORMING A SEALED CHANNEL OF A MICROFLUIDIC REACTOR AND A MICROFLUIDIC REACTOR COMPRISING SUCH CHANNEL ThalesNano Nanotechnológiai Zrt. (HU) 2007-06-28 WO disclosed
US-7189501-B2 Silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-13 US disclosed