SCHEMBL1674452

SCHEMBL1674452

CC(=O)C1(O)CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
KDM4E B2RXH2 1/20 0.33
CYP2C19 P33261 1/20 0.32
NPSR1 Q6W5P4 1/20 0.30
USP2 O75604 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
TSHR P16473 1/20 0.30
BLM P54132 1/20 0.30
CACNA2D1 P54289 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8228678 1.00 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2KDM4ECYP2C19NPSR1
Hydrochloric Acid SCHEMBL10437891 0.97 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2KDM4ECYP2C19
SCHEMBL2342427 0.97
Acetic Acid SCHEMBL11142798 0.95 FFAR3 (0.37) ALDH1A1SMN1; SMN2KDM4ECYP2C19USP2
SCHEMBL8230373 0.91
SCHEMBL11140873 0.86 KDM4E (0.34) KDM4ECYP2C19TSHR
SCHEMBL890235 0.84
Butyric Acid SCHEMBL11144951 0.81 FFAR3 (0.50) ALDH1A1CYP2C19LMNATSHR
Acetic Acid SCHEMBL27516411 0.78 CYP2C19 (0.39) ALDH1A1SMN1; SMN2KDM4ECYP2C19USP2
SCHEMBL16892247 0.76 POLB (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104437621-B Catalyst system and catalyzing for alkynol hydration reaction synthesis alpha-alcohol ketone 中国科学院化学研究所 2016-07-13 CN claimed
CN-104437621-A Catalytic system for synthesizing alpha-hydroxy ketone by alkynol hydration reaction CHINESE ACAD INST CHEMISTRY 2015-03-25 CN claimed
WO-2025003023-A1 METHOD FOR PRODUCING A CARBOXYLIC ACID EVONIK OPERATIONS GMBH (DE) 2025-01-02 WO disclosed
WO-2023191506-A1 METHOD FOR PREPARING CHLORINATED POLYVINYL CHLORIDE RESIN COMPOSITION 한화솔루션 주식회사 2023-10-05 WO disclosed
CN-116120295-A N-substituted imidazole formate derivative and application thereof 成都麻沸散医药科技有限公司 2023-05-16 CN disclosed
CN-113166303-B Preparation method of chlorinated polyvinyl chloride resin 韩华思路信(株) 2022-12-09 CN disclosed
CN-109843940-B Method for preparing chlorinated vinyl chloride resin 韩华化学株式会社 2022-05-17 CN disclosed
EP-3747869-A1 SUBSTITUTED IMIDAZOLE FORMATE DERIVATIVE AND USE THEREOF CHENGDU MFS PHARMA. CO., LTD. (CN) 2020-12-09 EP disclosed
US-20200369621-A1 SUBSTITUTED IMIDAZOLECARBOXYLATE DERIVATIVES AND THE USE THEREOF CHENGDU MFS PHARMA. CO., LTD. (CN) 2020-11-26 US disclosed
WO-2019149228-A1 SUBSTITUTED IMIDAZOLE FORMATE DERIVATIVE AND USE THEREOF 成都安诺晨创医药科技有限公司 2019-08-08 WO disclosed
CN-104370891-B A kind of 5-(butylene lactone-3-ethylidene)-2-aminooimidazole quinoline ketone compounds, preparation method and applications 中国农业大学 2016-09-07 CN disclosed
US-4374055-A ODORS, PERFUMES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1983-02-15 US disclosed
US-4359395-A Process for enhancing the organoleptic properties of perfumed articles using alkyl esters of 1-alkanolyl cycloalkanols INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-11-16 US disclosed
EP-0006305-B1 DERIVATIVES OF 4,5-DIHYDRO-4-OXOFURAN-2-CARBOXYLIC ACID, ESPECIALLY FOR USE AS HYPOLIPIDEMIC AGENTS, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, TETRAHYDROPYRAN-2,3,5-TRIONES USEFUL IN THE PREPARATION OF THE SAID DERIVATIVES AND A PROCESS FOR PREPARING THESE TETRAHYDROPYRAN-2,3,5-TRIONES AMERICAN HOME PRODUCTS CORPORATION (US) 1982-08-11 EP disclosed
US-4327749-A Alkyl esters of 1-alkanoyl cycloalkanols, process for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-05-04 US disclosed
US-4244958-A Hypolipidemic derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid AMERICAN HOME PRODUCTS CORPORATION (US) 1981-01-13 US disclosed
WO-1980000025-A1 DERIVATIVES OF 4,5-DIHYDRO-4-OXOFURAN-2-CARBOXYLIC ACID,PREPARATIONS AND USE THEREOF AND TETRAHYDROPYRAN-2,3,5-TRIONE INTERMEDIATES AMERICAN HOME PROD (US) 1980-01-10 WO disclosed
EP-0006305-A1 Derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid, especially for use as hypolipidemic agents, processes for their preparation, pharmaceutical compositions comprising them, tetrahydropyran-2,3,5-triones useful in the preparation of the said derivatives and a process for preparing these tetrahydropyran-2,3,5-triones AMERICAN HOME PRODUCTS CORPORATION (US) 1980-01-09 EP disclosed
US-4169202-A Process for preparing 4,5-dihydro-4-oxofuran-2-carboxylic acid derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1979-09-25 US disclosed
US-4111917-A POLYURETHANES W. R. GRACE & CO. (US) 1978-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200369621-A1 SUBSTITUTED IMIDAZOLECARBOXYLATE DERIVATIVES AND THE USE THEREOF SLC6A13, SLC6A11, SLC6A1 ALDH1A1 396/4885SMN1; SMN2 1497/4885KDM4E 520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.