Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 2/20 | 0.30 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.30 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16737961 | 0.81 | GAA (0.39) | MCHR1 | |
| Hydrochloric Acid SCHEMBL16737962 | 0.81 | GAA (0.39) | MCHR1 | |
| SCHEMBL17705194 | 0.81 | ALOX5AP (0.32) | ALOX5APFEN1HMGCR | |
| SCHEMBL17705201 | 0.78 | ALOX5AP (0.31) | ALOX5APFEN1 | |
| SCHEMBL16744711 | 0.77 | DHFR (0.32) | ALOX5APFEN1DHFRHMGCR | |
| SCHEMBL16737984 | 0.76 | MEP1B (0.31) | GCK | |
| SCHEMBL20149566 | 0.72 | MCHR1 (0.37) | MCHR1 | |
| SCHEMBL8279811 | 0.71 | MCHR1 (0.32) | MCHR1DHFRDCPS | |
| SCHEMBL30880496 | 0.66 | CYP19A1 (0.40) | MCHR1GCKDHFRDCPS | |
| SCHEMBL8282056 | 0.66 | ICMT (0.35) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9174974-B2 | Macrocyclic factor VIIa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-11-03 | — | — | US | disclosed |
| US-20150148313-A1 | MACROCYCLIC FACTOR VIIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148313-A1 | MACROCYCLIC FACTOR VIIA INHIBITORS | F7, F12, F5 | ALOX5AP 1805/4885FEN1 3532/4885MCHR1 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.